Results 191 to 200 of about 68,100 (329)
Movement Disorders Associated with 22q11.2 Microdeletion: A Scoping Review
Movement Disorders Clinical Practice, EarlyView.Abstract Background Movement disorders have recently emerged as important neurologic manifestations of the 22q11.2 microdeletion that affects nearly one in every 2000 live births. Objective We aimed to map the existing evidence regarding the spectrum, diagnosis and treatment, and etiopathogenesis of movement disorders associated with 22q11.2 ...
Nikolai Gil D. Reyes +6 more
wiley +1 more source
Genetic and Pathological Testing Attitudes for Parkinson's Disease in At‐Risk Relatives
Movement Disorders Clinical Practice, EarlyView.Abstract Background Parkinson's disease (PD) is increasingly recognized as a neurodegenerative disorder with a broad clinical spectrum and diverse biomarkers enabling early detection. α‐synuclein seed amplification assays (SAA) and genetic testing now allow identification of PD pathology in asymptomatic individuals.
Tal Weil +5 more
wiley +1 more source
Ow940 Zgis128[P(Dat-1)::Alpha-Synuclein::Yfp] | 2014-04-29T13:12:20+02:00
, 2018 Céline N. Martineau, Ellen A. A. Nollen
openalex +1 more source
A Biomarker‐Based Classification of Corticobasal Syndrome
Movement Disorders, EarlyView.Abstract Background Corticobasal syndrome (CBS) is a clinically defined syndrome with progressive movement and cortical dysfunction, caused by various underlying pathologies, most commonly tau‐predominant pathologies such as progressive supranuclear palsy and corticobasal degeneration, or Alzheimer's disease (AD).
Carla Palleis +13 more
wiley +1 more source
Ow940 Zgis128[P(Dat-1)::Alpha-Synuclein::Yfp] | 2014-03-01T19:22:04+01:00
, 2018 Céline N. Martineau, Ellen A. A. Nollen
openalex +1 more source
Reply: “PGRN Manifesting as Parkinson's Disease: Counseling and Treatment Implications”
Movement Disorders Clinical Practice, EarlyView.
Angelo Antonini +2 more
wiley +1 more source
LRRK2 as a Potential Disease‐Modifying Target in Sporadic Parkinson's Disease
Movement Disorders, EarlyView.Abstract A growing understanding of the role that leucine‐rich repeat kinase 2 (LRRK2) plays in Parkinson's disease (PD) supports continued focus on this enzyme as a therapeutic target for PD. Accumulating evidence suggests that there are phenotypic, neuropathologic, and biological similarities between sporadic PD (sPD) and familial forms in which ...
Anthony E. Lang +12 more
wiley +1 more source
Molecular Dynamics Simulations of Alpha-Synuclein Ensemble FRET Measurements from Different Force Fields [PDF]
, 2016 Reinhard Klement +4 more
openalex +1 more source
Constipation Is Linked to Neuroinflammation in Early Parkinson's Disease
Movement Disorders, EarlyView.Abstract Background Constipation is a risk factor for the onset and accelerated progression of Parkinson's disease (PD), but the mechanisms underlying this association are unknown. Neuroinflammation in PD has been demonstrated in postmortem and neuroimaging studies; however, its relationship with constipation has not been investigated.
Marta Camacho +8 more
wiley +1 more source