Screening of Some Indicators for Alpha-Thalassemia in Fujian Province of Southern China [PDF]
International Journal of General Medicine, 2021 Lin Zheng, Hailong Huang, Xiaoqing Wu, Linjuan Su, Qingmei Shen, Meiying Wang, Na Lin, Liangpu Xu Medical Genetic Diagnosis and Therapy Center of Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fujian Key ...
Zheng L +7 more
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A comprehensive case study of deep learning on the detection of alpha thalassemia and beta thalassemia using public and private datasets [PDF]
Scientific ReportsThis study explores the performance of deep learning models, specifically Convolutional Neural Networks (CNN) and XGBoost, in predicting alpha and beta thalassemia using both public and private datasets.
Muhammad Umar Nasir +7 more
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Alpha thalassemia genotypes in Kuwait [PDF]
BMC Medical Genetics, 2020 Background The frequency of the alpha thalassemia trait is approximately 40% in the Kuwaiti population, but there has been no comprehensive study of the prevalent alleles.
Adekunle Adekile +4 more
doaj +3 more sources
An analysis of the distribution and spectrum of alpha thalassemia mutations in Rasht City, North of Iran [PDF]
Frontiers in Pediatrics, 2023 BackgroundAlpha thalassemia is one of the most common hereditary hemoglobin disorders worldwide, particularly in the Middle East, including Iran.
Mona Asghari Ahmadabad +8 more
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Molecular and Haematological Characteristics of alpha-Thalassemia Deletions in Yogyakarta Special Region, Indonesia. [PDF]
Rep Biochem Mol Biol, 2021 Background alpha-Thalassemia is caused primarily by deletions of one to two alpha-globin genes and is characterized by absent or deficient production of alpha-globin protein.
Husna N, Handayani NSN.
europepmc +2 more sources
The Effect of Alpha Thalassemia, HbF and HbC on Haematological Parameters of Sickle Cell Disease Patients in Ibadan, Nigeria. [PDF]
Mediterr J Hematol Infect Dis, 2022 Background Sickle cell disease is a protean disease with limited data on Nigeria’s phenotypic and genetic variants. This study was conducted to provide baseline data on these variants by characterising the existing forms of sickle cell disease and ...
Fasola FA +5 more
europepmc +2 more sources
eJHaem, 2021 The genotype and phenotype correlation between coinheritance of heterozygous beta‐thalassemia with the alpha‐globin triplication is unclear. In this study we have investigated and reviewed alpha triplication frequency in beta‐thalassemia carriers, sickle
Mohammad Hamid +6 more
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Molecular Detection of Alpha Thalassemia: A Review of Prevalent Techniques. [PDF]
Medeni Med J, 2021 Alpha thalassemia (α-thalassemia) is an autosomal recessive disorder due to the reduction or absence of α globin chain production. Laboratory diagnosis of α-thalassemia requires molecular analysis for the confirmatory diagnosis.
Vijian D +4 more
europepmc +2 more sources
Clinical Utility of the Addition of Molecular Genetic Testing to Newborn Screening for Hemoglobinopathies for Confirmation of Alpha-Thalassemia Trait [PDF]
International Journal of Neonatal ScreeningHemoglobinopathies are commonly detected by newborn screening (NBS). One of the most difficult to accurately diagnose is alpha-thalassemia, which is indicated by the presence of hemoglobin (Hb) Barts on NBS.
Lisa M. Shook +2 more
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Alpha‐thalassemia. Case report alpha‐thalassemia in a Costa Rican family, A case report [PDF]
Clinical Case Reports, 2021 This case report highlights the importance for health care providers to be aware of the αlpha‐thalassemia syndromes, their relevance to clinical care and family counseling, appropriate diagnostic algorithm for definitive diagnosis.
Mariela Solano‐Vargas +2 more
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