Results 21 to 30 of about 28,973 (151)
Revista Brasileira de Hematologia e Hemoterapia, 2015 BACKGROUND: In sickle cell disease, the quantification of Hb A2 is important for the differential diagnosis between sickle cell anemia (Hb SS) and Hb S/ß0-thalassemia.OBJECTIVE: To determine Hb A2 levels as quantified by high performance liquid ...
Silvana Fahel da Fonseca +4 more
doaj +3 more sources
Third-generation sequencing identified a novel complex variant in a patient with rare alpha-thalassemia [PDF]
BMC PediatricsBackground Thalassemias represent some of the most common monogenic diseases worldwide and are caused by variations in human hemoglobin genes which disrupt the balance of synthesis between the alpha and beta globin chains.
Cong Zhou +5 more
doaj +2 more sources
Alpha thalassemia and alpha-MRE haplotypes in Uruguayan patients with microcytosis and hypochromia without anemia [PDF]
Genetics and Molecular Biology, 2021 Alpha thalassemia is the most common genetic disorder across the world, being the α-3.7 deletion the most frequent mutation. In order to analyze the spectrum and origin of alpha thalassemia mutations in Uruguay, we obtained a sample of 168 unrelated ...
Ana María Soler +7 more
doaj +1 more source
Association between Alpha-Thalassemia Carrier Prevalence and Incidence of COVID-19
Journal of Preventive, Diagnostic and Treatment Strategies in Medicine, 2022 BACKGROUND: The association between COVID-19 incidence and genetic underlying is an interesting issue. The possible association between thalassemia and COVID-19 is proposed.
Pathum Sookaromdee, Viroj Wiwanitkit
doaj +1 more source
Applications of Artificial Intelligence in Thalassemia: A Comprehensive Review
Diagnostics, 2023 Thalassemia is an autosomal recessive genetic disorder that affects the beta or alpha subunits of the hemoglobin structure. Thalassemia is classified as a hypochromic microcytic anemia and a definitive diagnosis of thalassemia is made by genetic testing ...
Khaled Ferih +7 more
doaj +1 more source
Iraqi Journal of Hematology, 2021 BACKGROUND: Iron deficiency is not common in thalassemia minor and nontransfusion dependent hemoglobinophaties. The majority of these patients have normal-to-high serum ferritin. OBJECTIVES: The aims of the study were to evaluate serum ferritin levels in
Mehdi Dehghani +4 more
doaj +1 more source
Thalassemia and hemoglobinopathy prevalence in a community-based sample in Sylhet, Bangladesh
Orphanet Journal of Rare Diseases, 2023 Background Inherited blood disorders affect 7% of the population worldwide, with higher prevalences in countries in the “thalassemia belt,” which includes Bangladesh.
Amanda S. Wendt +5 more
doaj +1 more source
Association Between Thalassemia and Leucocytic DNA Damage: A Pilot Study
Journal of Basic and Applied Research in Biomedicine, 2022 Objectives: Thalassemia with frequent blood transfusion was considered under oxidative stress because of the chance of iron overload. Patients with thalassemia trait with no blood transfusion might also suffered from oxidative stress because of ...
Yim Szeto, Charlton CHAN
doaj +2 more sources
İstanbul Tıp Fakültesi Dergisi, 2021 Objective: Alpha thalassemia is a common type of hemoglobinopathy that occurs as a result of deletions or point mutations in the alpha globin gene cluster.
Selma Demir +5 more
doaj +1 more source
Alpha-Hemoglobin Stabilizing Protein Gene Polymorphism (rs4499252 A/G) and its Association with Beta-Thalassemia Major in Iraqi Patients [PDF]
Archives of Razi Institute, 2022 Beta thalassemia (β-thalassemia) major is a genetic disorder of hemoglobin production that results in a diminished rate of synthesis of one or more of the globin chains causing variable degrees of anemia.
M Adnan Khalaf +3 more
doaj +1 more source