Results 111 to 120 of about 1,145,402 (246)
Comprehensive Physiology, Volume 16, Issue 1, February 2026.Vildagliptin and omarigliptin, dipeptidyl peptidase‐4 (DPP‐4) inhibitors, have differential effects on bone cells. Although vildagliptin improved the bone microstructure of high‐fat diet‐fed rats, it was unable to downregulate osteoclastogenesis or the expression of key osteoclast transcripts.
Ratchaneevan Aeimlapa +11 more
wiley +1 more source
Archipelago Method for Variant Set Association Test Statistics
Genetic Epidemiology, Volume 50, Issue 1, February 2026.ABSTRACT Variant set association tests (VSAT), especially those incorporating rare variants via variant collapse, are invaluable in genetic studies. However, unlike Manhattan plots for single‐variant tests, VSAT statistics lack intrinsic genomic coordinates, hindering visual interpretation.
Dylan Lawless +4 more
wiley +1 more source
Recent Insights Into Circulating Adipokines in Obesity: Systematic Review and Meta‐Analysis
Obesity Science &Practice, Volume 12, Issue 1, February 2026.ABSTRACT Background Adipokines are dysregulated in obesity and exacerbate proinflammatory conditions. Although several studies have investigated adipokine levels in obesity, their findings have been inconsistent, leaving the precise nature of these alterations uncertain.
Sunita Sunita +10 more
wiley +1 more source
An investigation of the protective effect of alpha+-thalassaemia against severe Plasmodium falciparum amongst children in Kumasi, Ghana [PDF]
Background: The alpha+-thalassaemias are the most common monogenic disorders of humans, characterised by microcytic and hypochromic anaemia. Their high frequency reflects selective advantage against death from Plasmodium falciparum malaria.
Opoku-Okrah, C., Opoku-Okrah, C.
core
Vaimse arengu mahajäämuse geneetilised põhjused: X-liiteline vaimse arengu mahajäämus [PDF]
, 2007 Üheks kõige sagedasemaks raske puude põhjuseks lastel ja noortel on vaimse arengu mahajäämus (VAM). Vaatamata sellele, et välja on töötatud palju erinevaid uurimis meetodeid, jääb enamik neist patsientidest praegugi veel täpse diagnoosita.
Kurg, Ants +3 more
core +2 more sources
Insulin resistance, impaired glucose tolerance and alpha-thalassemia carrier state
Journal of Diabetes and Metabolic Disorders, 2015 BackgroundThis study was designed to determine relationship between the glucose metabolism disorder (the insulin resistance and the impaired glucose tolerance) and α-thalassemia.MethodsIn this historical cohort study, 80Alpha-thalassemia carriers and 80 ...
A. Bahar +5 more
semanticscholar +1 more source
Aging Cell, Volume 25, Issue 2, February 2026.This work proposes ferroptosis as a mechanistic driver of age‐related muscle dysfunction, whereby iron dyshomeostasis and impaired antioxidant capacity promote lipid peroxidation, and eventually trigger ferroptosis, leading to muscle wasting, and ultimately contributing to weakness and functional decline with aging.
Rola S. Zeidan +6 more
wiley +1 more source
Research in Molecular Medicine, 2017 Alpha Thalassemia is one of the most prevalent disorders worldwide with a [T1] high carrier rate in Mazandaran province (north of Iran). Carriers of --MED double gene deletion are at risk of having a child with hemoglobin haemoglobin[T2]
Hossein Jalali +3 more
doaj
Effect of sex class on the levels of some biochemical variables in thalassemia patients
Tikrit Journal of Pure Science, 2019 The study was conducted at Azadi Teaching Hospital - Thalassemia Center for the period from 1/10/2017 to 1/4/2018. It included 60 patients including 30 males and 30 females, as well as control group which included 20 Healthy people were all 10 to 21 ...
Khalaf N. Mohammed, Mossa M. Marbut
doaj +1 more source
Journal of Laboratory Physicians, 2015 Context: The prevention and control of thalassemia in Thailand focus on the appropriate diagnosis with a simple, cheap, and practical tool for any staff to use.
Y. Sudjaroen
semanticscholar +1 more source