Results 11 to 20 of about 1,304,324 (179)
Hematological analysis of alpha-thalassemia: A single-center, retrospective clinical study. [PDF]
PLoS ONEObjectivesTo determine the optimal cutoffs of the three indicators (MCV, MCH and HbA2) for alpha-thalassemia screening and to evaluate the validity of these indicators in Fujian Province, China.MethodsWe conducted a retrospective analysis on the results ...
Lin Zheng +7 more
doaj +2 more sources
Revista Brasileira de Hematologia e Hemoterapia, 2015 BACKGROUND: In sickle cell disease, the quantification of Hb A2 is important for the differential diagnosis between sickle cell anemia (Hb SS) and Hb S/ß0-thalassemia.OBJECTIVE: To determine Hb A2 levels as quantified by high performance liquid ...
Silvana Fahel da Fonseca +4 more
doaj +2 more sources
Genetic Analysis of Alpha-Thalassemia Mutations in Thi-Gar Province, Iraq [PDF]
Archives of Razi Institute, 2022 The prevalence of alpha-thalassemia as a major health problem in the south of Iraq has highlighted the necessity of investigations and screening of patients with thalassemia.
A. H Odah Al-Musawi +2 more
doaj +2 more sources
Turkish Journal of Hematology, 2015 INTRODUCTION: Alpha thalassemia syndromes are caused by mutations on one or more of the four α-globin genes. Mutations could be either more commonly deletional or non-deletional. As some deletions (3.7 and 4.2) cause α+-thalassemia, some cause (
Zeynep Karakaş +11 more
doaj +2 more sources
Third-generation sequencing identified a novel complex variant in a patient with rare alpha-thalassemia [PDF]
BMC PediatricsBackground Thalassemias represent some of the most common monogenic diseases worldwide and are caused by variations in human hemoglobin genes which disrupt the balance of synthesis between the alpha and beta globin chains.
Cong Zhou +5 more
doaj +2 more sources
Alpha thalassemia and alpha-MRE haplotypes in Uruguayan patients with microcytosis and hypochromia without anemia [PDF]
Genetics and Molecular Biology, 2021 Alpha thalassemia is the most common genetic disorder across the world, being the α-3.7 deletion the most frequent mutation. In order to analyze the spectrum and origin of alpha thalassemia mutations in Uruguay, we obtained a sample of 168 unrelated ...
Ana María Soler +7 more
doaj +1 more source
Association between Alpha-Thalassemia Carrier Prevalence and Incidence of COVID-19
Journal of Preventive, Diagnostic and Treatment Strategies in Medicine, 2022 BACKGROUND: The association between COVID-19 incidence and genetic underlying is an interesting issue. The possible association between thalassemia and COVID-19 is proposed.
Pathum Sookaromdee, Viroj Wiwanitkit
doaj +1 more source
Alpha-Thalassemia: Diversity of Clinical Phenotypes and Update on the Treatment
Thalassemia Reports, 2022 One of the more common single-gene disorders worldwide is α-thalassemia, carriers of which are found at variable frequencies (>1%) across all tropical and subtropical countries.
D. Songdej, S. Fucharoen
semanticscholar +1 more source
Journal of clinical laboratory analysis (Print), 2021 Stroke is a devastating complication of sickle cell anemia (SCA) and can be predicted through abnormally high cerebral blood flow velocity using transcranial Doppler Ultrasonography (TCD).
O. Ojewunmi +5 more
semanticscholar +1 more source
American journal of hematology/oncology, 2023 This systematic literature review assessed the global prevalence and birth prevalence of clinically significant forms of alpha‐ and beta‐thalassemia. Embase, MEDLINE, and the Cochrane Library were searched for observational studies published January 1 ...
K. Musallam +8 more
semanticscholar +1 more source