Results 41 to 50 of about 1,145,402 (246)
Thalassemia, a human blood disorder
Brazilian Journal of Biology, 2021 A group of inherited blood defects is known as Thalassemia is among the world’s most prevalent hemoglobinopathies. Thalassemias are of two types such as Alpha and Beta Thalassemia. The cause of these defects is gene mutations leading to low levels and/or
F. Shafique +8 more
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Hematological and Genetic Predictors of Daytime Hemoglobin Saturation in Tanzanian Children with and without Sickle Cell Anemia. [PDF]
, 2013 Low hemoglobin oxygen saturation (SpO2) is common in Sickle Cell Anemia (SCA) and associated with complications including stroke, although determinants remain unknown.
Cox, Sharon E +4 more
core +5 more sources
Revealing the molecular signatures of host-pathogen interactions. [PDF]
, 2011 Advances in sequencing technology and genome-wide association studies are now revealing the complex interactions between hosts and pathogen through genomic variation signatures, which arise from evolutionary co ...
C Herdtweck +53 more
core +18 more sources
Revista Brasileira de Hematologia e Hemoterapia, 2015 BACKGROUND: In sickle cell disease, the quantification of Hb A2 is important for the differential diagnosis between sickle cell anemia (Hb SS) and Hb S/ß0-thalassemia.OBJECTIVE: To determine Hb A2 levels as quantified by high performance liquid ...
Silvana Fahel da Fonseca +4 more
doaj +1 more source
Mediterranean Journal of Hematology and Infectious Diseases, 2023 Background and objectives. Investigating the prevalence of thalassemia in the Vietnamese population, building a clinical decision support system for prenatal screening for thalassemia. Methods.
Danh Cuong Tran +7 more
doaj +1 more source
Update in Laboratory Diagnosis of Thalassemia
Frontiers in Molecular Biosciences, 2020 Alpha- and β-thalassemias and abnormal hemoglobin (Hb) are common in tropical countries. These abnormal globin genes in different combinations lead to many thalassemic diseases including three severe thalassemia diseases, i.e., homozygous β-thalassemia ...
Thongperm Munkongdee +4 more
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Thalassemia intermedia as a result of heterozygosis for ß0-thalassemia and aaaanti-3.7/aa genotype in a Brazilian patient [PDF]
Brazilian Journal of Medical and Biological Research, 2003 We report a case in which the interaction of heterozygosis for both the ß0-IVS-II-1 (G->A) mutation and the aaaanti-3.7 allele was the probable cause for the clinical occurrence of thalassemia intermedia.
E.M. Kimura +4 more
doaj +1 more source
Journal of clinical laboratory analysis (Print), 2021 Thalassemia is a group of inherited autosomal recessive hemolytic anemia disease caused by reduced or absent synthesis of globin chain/chains of hemoglobin. Only few studies showed the molecular characterization of α‐ and β‐thalassemia in Meizhou city of
Heming Wu +3 more
semanticscholar +1 more source
Alpha Thalassemia in Istanbul: Distribution of Deletions in Alpha-globin Gene Cluster
Genel Tıp DergisiBackground/Aims: Alpha thalassemia is an autosomal recessive congenital disease resulting from a globin protein disorder encoded by genes in the alpha thalassemia gene cluster.
Fatma Nihal Öztürk
doaj +1 more source
Relationship Between Alpha+-Thalassaemia and Glutathione-S-Transferases Polymorphisms in Children with Severe Malaria in Tanzania [PDF]
, 2013 Alpha+-thalassaemia is well known for conferring partial protection to against severe malaria. On the other, Glutathione –S-transferase (GST) polymorphism has recently been associated to severe malaria in children.
Balthazary, Sakurani +5 more
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