Results 101 to 110 of about 4,635,456 (297)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
An Approach to Nuclear Fusion Utilizing the Dynamics of High-Density Electrons and Neutrals, Part I
PlasmaAn approach to achieve nuclear fusion utilizing the formation of high densities of electrons and neutrals is described. The abundance of low energy free electrons produces intense electric fields that reduce the Coulomb barrier in nuclear fusion ...
Alfred YiuFai Wong, Chun-Ching Shih
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Degenerate Mobilities in Phase Field Models are Insufficient to Capture Surface Diffusion
, 2015 Phase field models frequently provide insight to phase transitions, and are robust numerical tools to solve free boundary problems corresponding to the motion of interfaces.
Lee, Alpha A +2 more
core +1 more source
, 2017 Why do investors entrust active mutual fund managers with large sums of money while receiving negative excess returns on average? Our explanation is that investors have a coarser information set than fund managers which leads them to systematically misinterpret managers' skill.
Müller, Marcel +2 more
openaire +3 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Mitochondrial DNA. Part B. ResourcesLuciogobius parvulus (Snyder, 1909) is distributed in restricted areas of Japan and South Korea. Here, we report the first complete mitochondrial genome of this species.
Min-Soo Kim +6 more
doaj +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Mìžnarodnij Endokrinologìčnij ŽurnalBackground. Cardiovascular diseases remain the leading cause of death in both men and women in industrialized countries. They encompass a variety of conditions, including cerebrovascular disease, peripheral arterial disease, atherosclerosis, and deep ...
Fidel Krasniqi +2 more
doaj +1 more source
Detecting and Quantifying Mind Wandering during Simulated Driving
Frontiers in Human Neuroscience, 2017 Mind wandering is a pervasive threat to transportation safety, potentially accounting for a substantial number of crashes and fatalities. In the current study, mind wandering was induced through completion of the same task for 5 days, consisting of a 20 ...
Carryl L. Baldwin +5 more
doaj +1 more source