Results 71 to 80 of about 4,902,736 (350)
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Historical Development of the Olympic Movement [PDF]
The Olympic Movement is a term that covers all areas related to the phenomenon of Olympism. From its creation, the Olympic Movement has had to follow and to respond to numerous challenges and changes of the 20th and 21st century.
Violeta Šiljak, Dejan Djurovic
doaj
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
XEN Glaucoma Implant with Mitomycin C 1-Year Follow-Up: Result and Complications
Purpose. To evaluate gel microstent (XEN, Aquesys, Inc) for treatment of primary open angle glaucoma (POAG). Methods. In this prospective interventional study, 13 eyes with POAG underwent XEN implantation with subconjunctival mitomycin-C.
Ahmed Galal +3 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Single-Use Technology Today – A Cornucopia of Applications
Whether for classic biologics or advanced therapy medicinal products (ATMPs), laboratory applications, small-scale or large-scale productions, single-use technology (SUT), and its associated consumables are used everywhere.
Diego R. Schmidhalter +2 more
doaj +1 more source
Medicina Geral e Familiar em Portugal
Nas últimas décadas, tem-se assistido em Portugal ao desenvolvimento da especialidade de Medicina Geral e Familiar (MGF), à semelhança daquilo que tem ocorrido em outros países europeus.
Ana Costa, Raquel Pedro, Sara Magalhães
doaj +1 more source
Introduction It has been suggested that transcranial alternating current stimulation (tACS) at both alpha and beta frequencies promotes motor function as well as motor learning.
Taiki Harada +6 more
doaj +1 more source
Determining the Absorbed Dose of Alpha Radiation due to Inhalation Radon Gas and Its Derivatives in Human Lung Using MCNPX 2.6.0 Simulation Model by Jafari et al. In Khorasan Razavi, Summer 2019 [PDF]
Background & Objective: People who work in closed and underground environments such as mines get radioactive gases into their respiratory system due to the concentration in the air.
Farhad Mohmmad Jafari, Javad Bahmani
doaj

