Results 51 to 60 of about 30,247,731 (144)
Why do specific proteins accumulate on “non‐fouling” surfaces? Quantitative proteomics and structural analysis reveal surface‐exposed arginine as the key molecular determinant. ABSTRACT The protein corona determines the biocompatibility of medical devices, yet predicting its composition on anti‐fouling surfaces remains challenging.
Ayano Nomura +5 more
wiley +1 more source
Deficiency of α-1-antitrypsin influences systemic iron homeostasis
Andrew J Ghio,1 Joleen M Soukup,1 Judy H Richards,1 Bernard M Fischer,2 Judith A Voynow,2 Donald E Schmechel31US Environmental Protection Agency, Chapel Hill, NC, USA; 2Division of Pediatric Pulmonary Medicine, Department of Pediatrics,3Joseph and ...
Soukup JM +5 more
core
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang +6 more
wiley +1 more source
ABSTRACT In persistent HPS‐related hypoxemia after LT, prolonged VV‐ECMO can serve as a bridge to recovery when conventional oxygenation strategies fail. Serial contrast‐enhanced echocardiography and multidisciplinary management may support weaning decisions and the management of ECMO‐related complications.
Paweł Topolewski +9 more
wiley +1 more source
Danielle M Dunlea, Laura T Fee, Thomas McEnery, Noel G McElvaney, Emer P Reeves Irish Centre for Genetic Lung Disease, Department of Medicine, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin, Ireland Abstract: Alpha-1 antitrypsin (AAT) is
McEnery T +4 more
core
Large Undifferentiated Sarcoma of the Liver: A Rare Case Report and Literature Review
ABSTRACT Undifferentiated embryonal sarcoma of the liver (UESL) is a rare pediatric malignancy requiring prompt histopathological diagnosis. Neoadjuvant chemotherapy followed by extended right hepatectomy can achieve complete tumor necrosis with negative margins. A multidisciplinary approach is essential for favorable outcomes in pediatric UESL.
Hanzala Zahid +7 more
wiley +1 more source
Irina Petrache1, Joud Hajjar1, Michael Campos21Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA; 2Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, Miller School of Medicine ...
Campos, Michael +5 more
core
ABSTRACT Background Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and remains a major cause of cancer‐related mortality worldwide. Its poor clinical outcomes are largely attributed to late‐stage diagnosis and the limited accuracy of currently available diagnostic and prognostic biomarkers.
Jana Hamad +2 more
wiley +1 more source
Generation and characterisation of transgenic zebrafish expressing human alpha-1-antitrypsin
The Z variant of α1-antitrypsin (Z-AAT) is the most common “severe” deficiency allele of α1-antitrypsin. It affects approximately 2% to 5% of Caucasians of European descent [1-3].
Yip, Evelyn Lai Si (3770644)
core +1 more source
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka +4 more
wiley +1 more source

