Results 101 to 110 of about 14,550 (189)

Safety and efficacy of alpha-1-antitrypsin augmentation therapy in the treatment of patients with alpha-1-antitrypsin deficiency

, 2009
Irina Petrache1, Joud Hajjar1, Michael Campos21Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA; 2Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, Miller School of Medicine ...
Campos, Michael, Michael Campos, Irina Petrache, Joud Hajjar, Hajjar, Joud, Petrache, Irina   +5 more
core  

ABO Incompatible Deceased Donor Liver Transplants in Infants (Age < 1 Year): A Single‐Center Experience

Pediatric Transplantation, Volume 30, Issue 6, June 2026.
The liver transplant waitlist mortality for infants (age < 1 year) is currently the highest among all ages. ABO incompatible (ABOi) liver‐transplantation is one of the strategies to increase transplantation rate in infants and can be safely performed in children less than 1 year of age without plasmapheresis, with excellent long‐term outcomes. ABSTRACT
Heli Bhatt, Sarah Kizilbash, Claudia Cohn, Oyedele Adeyi, Daniel Waller, David M. Vock, Gwenyth Fischer, Joseph Resch, Andrew Adams, Srinath Chinnakotla   +9 more
wiley   +1 more source

Improving adherence to alpha-1 antitrypsin deficiency screening guidelines using the pulmonary function laboratory

, 2017
Landy V Luna Diaz,1 Isabella Iupe,1 Bruno Zavala,1 Kira C Balestrini,1 Andrea Guerrero,1 Gregory Holt,1,2 Rafael Calderon-Candelario,1,2 Mehdi Mirsaeidi,1,2 Michael Campos1,21Miami Veterans Administration Medical Center, Miami, FL, 2Division of Pulmonary,
Luna Diaz LV, Calderon-Candelario R, Zavala B, Guerrero A, Balestrini KC, Campos M, Iupe I, Mirsaeidi M, Holt G   +8 more
core  

When ‘Liver Enzymes’ Are Not Hepatic: Late‐Onset Pompe Disease

Medical Journal of Australia, Volume 224, Issue 6, June 2026.
ABSTRACT Elevated liver function tests are commonly attributed to hepatic disease but may reflect extrahepatic pathology. We describe the case of an 18‐year‐old athletic woman with a 2‐year history of elevated aspartate aminotransferase (AST), alanine aminotransferase (ALT) and creatine kinase (CK) levels, initially investigated extensively for hepatic
Shauna Madigan, Georgina England, Wayne Rankin   +2 more
wiley   +1 more source

The delay effect of sulfur mustard gas on phenotype and plasma alpha-1-antitrypsin activity in war victim patients

مجله دانشگاه علوم پزشکی گرگان, 2010
Background and Objective: Alpha-1 antitrypsin deficiency is recognized as a etiological base in lung injury. Therefore this study was performed to determine plasma level of alpha-1 antitrypsin in war victims exposed to sulfur mustard gas.
Majid Shohrati (PhD), Navvab Shamspour (MSc), Afshin Mohsenifar (PhD), Mostafa Ghanei (MD)   +3 more
doaj  

The Alpha 1 antitrypsin deficiency - etiology, symptoms in various organs, diagnosis, treatment, prognosis

Journal of Education, Health and Sport
Introduction: Alpha-1 antitrypsin (AAT) is a glycoprotein produced by liver, belonging to the serine protease inhibitor family. Alpha-1 antitrypsin deficiency (AATD) is very common autosomal recessive genetic disease caused by point mutation in ...
Dawid Kościołek, Michał Urbaś, Martyna Kępczyk, Aleksandra Kościołek, Kaja Surowiecka, Jakub Misiak, Miłosz Ojdana, Konrad Szalbot, Mikołaj Tokarski, Natalia Marczak   +9 more
doaj   +1 more source

Therapeutics: Gene Therapy for Alpha-1 Antitrypsin Deficiency

, 2017
This review seeks to give an overview of alpha-1 antitrypsin deficiency, including the different disease phenotypes that it encompasses. We then describe the different therapeutic endeavors that have been undertaken to address these different phenotypes.
Flotte, Terence R., Gruntman, Alisha M
core   +1 more source

Liver Disease in Alpha-1-Antitrypsin Deficiency

, 2019
Alpha-1-antitrypsin deficiency is a hereditary disorder characterized by a deficiency of the primarily liver-produced enzyme alpha-1-antitrypsin. In children, it remains the most common genetic cause of liver disease.
Alice Turner, Awan, Zoya, Turner, Alice, Zoya Awan   +3 more
core   +1 more source

Liver:: Alpha-1-Antitrypsin Deficiency.

, 1900
Alpha-1-antitrypsin deficiency. COMMENT: Bile stasis and a micronodular cirrhosis are seen in this example of enzyme deficiency disease.
MUSC Department of Pathology and Laboratory Medicine
core  

Pulmonary artery aneurysm as a rare manifestation of Alpha-1 antitrypsin deficiency

Respiratory Medicine Case Reports
Alpha-1 antitrypsin is a relatively well-known genetic disease known to primarily affect the lungs and liver. Extrapulmonary manifestations of this disease have been reported, including vascular aneurysms.
Mark A. Colantonio, Sanjana Aggarwal, Himanshu Deshwal   +2 more
doaj   +1 more source