Results 41 to 50 of about 254,283 (268)

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

FEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii, Edoardo Andrea Cutolo, Daniele Montepietra, Claudia Battarra, Roberto Caferri, Stefano Capaldi, Zeno Guardini, Luca Dall'Osto, Roberto Bassi   +8 more
wiley   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

A Neural Network Architecture for Maximizing Alpha in a Market Timing Investment Strategy

IEEE Access
In finance, assuming more risk often corresponds to the expectation of higher, compensating returns. In this setting, alpha stands out as one of the most prevalent and refined measures of risk-adjusted return ever postulated, allowing for the estimation ...
Javier H. Ospina-Holguin, Ana M. Padilla-Ospina   +1 more
doaj   +1 more source

Constructing portfolios using stable distributions: The case of S&P 500 sectors exchange-traded funds

Machine Learning with Applications, 2022
Portfolio construction is an important practical problem in finance. In the traditional approach, introduced by Markowitz, one assumes normally distributed returns and constructs a portfolio with a minimum risk (measured by the standard deviation of ...
Andrei Vasiukevich, Eugene Pinsky
doaj   +1 more source

Financial literacy and behavioural biases of individual investors: empirical evidence of Pakistan stock exchange [PDF]

Journal of Economics Finance and Administrative Science, 2020
Purpose – Financial literacy is a crucial element of financial decision-making, exerting significant influence on the behaviour of individual investors, while making budgetary, house financing, stock investing and retirement planning decisions.
Nosheen Rasool, Safi Ullah
doaj   +1 more source

Analisis Pengaruh Non Performing Loan, Dana Pihak Ketiga, terhadap Pembiayaan Akad Mudharabah di Bank Syariah [PDF]

, 2017
Penelitian ini bertujuan untuk mengetahui pengaruh Non Performing Finance, dan Dana Pihak Ketiga terhadap pemberian pembiayaan mudharabah. Sampel yang digunakan adalah NPF, DPK dan Mudharabah, dari bulan januari 2012 sampai Desember 2015.
Pradesyah, R. (Riyan)
core  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

A Model for Identifying and Analyzing of Strategy Implementation Barriers [PDF]

مطالعات مدیریت راهبردی, 2016
This research designs a model for Identifying and Analyzing of Strategy Implementation Barriers in Saman Bank. At first, the theoretical principals and concepts are reviewed and then measuring indicators of each index and dimension are derived by the ...
Mohammad Ali Babayi Zekilaki, Masoumeh Hosseinzadeh Shahri, Mahin Rahimpour, Arman Ahmadizad   +3 more
doaj  

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source