Results 161 to 170 of about 345,950 (317)

Prolonged response to PIK3CA inhibition in an advanced hormone-positive breast cancer patient with 3 mutations in the alpha subunit of PI-3 kinase. [PDF]

Oncologist
Merose R, Leibowitz R.
europepmc   +1 more source

NMR backbone and methyl assignment of G-protein alpha i,1 subunit bound to GDP

, 2019
David Goričanec, Franz Hagn
openalex   +1 more source

Delta Opioid Receptors within the Cortico‐Thalamic Circuitry Underlie Hyperactivity Induced by High‐Dose Morphine

Advanced Science, EarlyView.
Morphine activates the excitatory cingulate cortex–intermediate rostrocaudal division of zona incerta (Cg‐ZIm) pathway to drive hyperlocomotion in mice. Inhibiting the Cg‐ZIm pathway attenuates both acute and chronic morphine‐induced hyperlocomotion, while its activation mimics morphine's motor effects.
Chun‐Yue Li, Huiqian Huang, Xiao‐Fan Shen, Ke‐Lei Cao, Di Zheng, Yi Zhu, Shi‐Ze Xie, Xiao‐Dan Yu, Hao Wang, Jia‐Dong Chen, Jie Shi, Yue Li, Min Yan, Xiao‐Ming Li   +13 more
wiley   +1 more source

The Na⁺-K⁺-ATPase alpha subunit is an entry receptor for white spot syndrome virus. [PDF]

mBio
Zhou J, Zhang H, Wu G, Zhang Y, Aweya JJ, Tayyab M, Zhu J, Zhang Y, Yao D.   +8 more
europepmc   +1 more source

Acroamine A, a 2-Amino Adenine Alkaloid from the Marine Soft Coral Acrozoanthus australiae and Its Semisynthetic Derivatives That Inhibit cAMP-Dependent Protein Kinase A Catalytic Subunit Alpha

Sarath P. D. Senadeera, Dongdong Wang, Brice A. P. Wilson, Emily A. Smith, Antony Wamiru, Juliana A. Martinez Fiesco, Lin Du, Ping Zhang, Barry R. O’Keefe, John A. Beutler   +9 more
openalex   +1 more source

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

Advanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang, Chaohu Wang, Jun Fan, Zexin Chen, Haoying Yu, Yawen Bai, Tingcheng Zhang, Qianchao Zhu, Yiwen Feng, Peirong Niu, Jiaqian Chen, Liping Yang, Xueying Li, Lei Yu, Songtao Qi, Yi Liu   +15 more
wiley   +1 more source

Altering Active-Site Loop Dynamics Enhances Standalone Activity of the Tryptophan Synthase Alpha Subunit. [PDF]

ACS Catal
Duran C, Kinateder T, Hiefinger C, Sterner R, Osuna S.   +4 more
europepmc   +1 more source

Targeting the alpha subunit of IL-3 receptor (CD123) in patients with acute leukemia. [PDF]

Hum Vaccin Immunother, 2020
Aldoss I, Clark M, Song JY, Pullarkat V.
europepmc   +1 more source

Characterization of Gf a Drosophila trimeric G protein alpha subunit

, 2012
Naureen Quibria
openalex   +1 more source

CCDC41 Drives Oocyte Meiotic Progression by Promoting Rab11a/Rab7‐Positive Vesicle Fusion with Target Membranes

Advanced Science, EarlyView.
CCDC41 is essential for meiotic maturation in mouse oocytes through regulating Rab7‐positive endosomes fusion with lysosomes and Rab11a‐positive vesicle fusion with the plasma membrane. Abstract Coiled‐coil domain‐containing protein 41 (CCDC41), a core component of centriolar distal appendages involved in centriole assembly and ciliary vesicle docking,
Ying Tian, Jiatong Li, Jingyi Kang, Xiangning Xu, Bicheng Wang, Shuo Lou, Jingyu Li, Yuying Yang, Yanbing Zhang, Yangzi Zheng, Jing Weng, Yuanjing Liang, Wei Ma   +12 more
wiley   +1 more source