Results 161 to 170 of about 566,712 (212)

Pure alpha subunit-secreting pituitary tumors

Journal of Neurosurgery, 1983
✓ The authors describe six patients with pituitary macroadenomas hypersecreting only the alpha subunit of the glycoprotein hormones. These patients had been previously diagnosed as having “non-functioning chromophobe adenomas.” All of the patients had visual field abnormalities and partial hypopituitarism. The elevated serum alpha concentrations showed
A, Klibanski, E C, Ridgway, N T, Zervas
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II. Immunochemical studies on alpha crystallin subunits

Experimental Eye Research, 1972
Abstract Carboxymethylated alpha crystallin subunits yield a clearer separation of the acidic and basic subunit molecules than native alpha crystallin subunits. A minimum of four distinct subunit molecules could be observed in all fractionation procedures tested.
D, Zouzias, W, Manski
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Alpha-subunit-producing pituitary adenomas

Virchows Archiv A Pathological Anatomy and Histopathology, 1986
Immunohistological techniques demonstrate the alpha-subunit of glycoprotein hormones in the majority of endocrine-inactive, undifferentiated pituitary adenomas and pituitary oncocytomas. In about one-fifth of endocrine-active adenomas, the alpha-subunit is produced in combination with either adrenocorticotropic hormone or prolactin, and it is found in ...
A M, Landolt, P U, Heitz
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Structure of Human Luteinizing Hormone Alpha Subunit

Endocrine Research Communications, 1978
Structural studies have substantiated the concept that the glycoprotein hormones consist of a "common" alpha subunit and "hormone-specific" beta subunit. Despite this, consensus is still lacking concerning certain portions of the amino acid sequences, including alignment of residues 81--82 in the alpha subunit.
H T, Keutmann   +3 more
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Evidence for oligomeric forms of transducins alpha subunit: Formation of intermolecular alpha-alpha disulfide linkages

Biochemical and Biophysical Research Communications, 1989
Transducin, the retinal G-protein, is a heterotrimeric protein composed of alpha, beta and gamma subunits. Intermolecular disulfide linkages between the alpha-subunits of transducin molecules are spontaneously formed when the purified G-protein is placed in a non-reducing buffer system.
M, Wessling-Resnick, G L, Johnson
openaire   +2 more sources

Identification of subunit contact sites on the .alpha.-subunit of lutropin

Biochemistry, 1991
Peptides corresponding to the entire sequence of the alpha-subunit of the human glycoprotein hormones were synthesized by using standard solid-phase procedures. Purified peptides were incubated in the presence of alpha- and beta-subunits of bovine lutropin, and subunit recombination was monitored by difference spectroscopy, reverse-phase high-pressure ...
S R, Krystek, J A, Dias, T T, Andersen
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Alpha-Subunit Secreting Pituitary Tumors

1997
The pituitary glycoprotein hormones, TSH, FSH, and LH are comprised of two separate noncovalently bound subunits, alpha and beta. The alpha subunit is identical in all of the hormones. The β-subunit is unique for each and confers the specific immunologic and functional activity.
Tamis M. Bright, E. Chester Ridgway
openaire   +1 more source

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