Results 91 to 100 of about 39,321 (195)

An Immunological and Molecular Study to Investigate the Genes (β-globin and HBA1F) in Patients with Thalassemia in Najaf Governorate

Journal of Preventive, Diagnostic and Treatment Strategies in Medicine
BACKGROUND: Thalassemia, a hereditary blood disorder, poses a significant health challenge globally. This study delves into the prevalence and characteristics of thalassemia, emphasizing the need for enhanced awareness and diagnostic measures ...
Hussein Fadi Ibrahim, Azhar Salih Mahdi, Sabah N. Mohammed Al Fatlawi, Ahmed Obaid Harrewee, Raghdah Maytham Hameed   +4 more
doaj   +1 more source

Identification of α°-thalassaemia (–SEA) using an enzyme-linked immunosorbent assay (ELISA) for embryonic zeta-globin chain detection – a preliminary study [PDF]

, 2006
Objectives: This study aimed to evaluate the UBI MAGIWELTM ζ-GLOBIN ELISA Kit for the presumptive diagnosis of αo-thalassaemia. The ELISA results obtained were confirmed by molecular characterisation of αo-thalassaemia using a Duplex-PCR.
George, Elizabeth, Hassan, R., Lim, E. J., Tan, K. L., Tan, Mary Anne Jin Ai, Wee, Y. C., Zakaria, Z.   +6 more
core  

An investigation of the protective effect of alpha+-thalassaemia against severe Plasmodium falciparum amongst children in Kumasi, Ghana [PDF]

Background: The alpha+-thalassaemias are the most common monogenic disorders of humans, characterised by microcytic and hypochromic anaemia. Their high frequency reflects selective advantage against death from Plasmodium falciparum malaria.
Opoku-Okrah, C., Opoku-Okrah, C.
core  

Preimplantation Genetic Diagnosis for Alpha Thalassemia: Experience in Siriraj Hospital

Siriraj Medical Journal, 2008
Objective: Detection of fetal thalassemia using preimplantation genetic diagnosis (PGD) can make a diagnosis before pregnancy so termination of pregnancy in that patient is eliminated.
Japarath Prechapanich, Roungsin Choavaratana, Orawan Makemaharn, Chompunut Kanjanakorn, Wanna Thongnoppakhun, Chanin Limwongse   +5 more
doaj  

Frequency of alpha-thalassemia in Greece.

American journal of hematology, 1986
Using hematological and gene mapping techniques, a cord blood survey was carried out to estimate the frequency of alpha-thalassemia in the Greek population. Out of 227 newborns studied, 16 (7.05%) were found by gene mapping to be alpha-thalassemia 2 heterozygotes (-alpha/alpha alpha), and of these only two had increased levels of hemoglobin Bart's in ...
KANAVAKIS, E, TZOTZOS, S, LIAPAKI, A, METAXOTOUMAVROMATI, A, KATTAMIS, C   +4 more
openaire   +2 more sources

Prevalence of hemoglobinopathies in premarriage individuals referred to Babolsar, Iran (2006-09)

مجله دانشگاه علوم پزشکی گرگان, 2012
Background and Objective: According to world health organization statistics, at least 5.2% of world population is carrier for a main hemoglobin disorder. Previous reports showed that more than 10% of people are carrier for beta-thalassemia Northern Iran.
Valizadeh F (MD), Mousavi A (BSc), Hashemi-Soteh MB (PhD)   +2 more
doaj  

Molecular patterns of alpha-thalassemia in the kingdom of Saudi Arabia: identification of prevalent genotypes and regions with high incidence. [PDF]

Thromb J, 2023
Alhuthali HM, Ataya EF, Alsalmi A, Elmissbah TE, Alsharif KF, Alzahrani HA, Alsaiari AA, Allahyani M, Gharib AF, Qanash H, Elmasry HM, Hassanein DE.   +11 more
europepmc   +1 more source

Hematological Indices of Parents in Non-Immune Hydrops Fetalis Pregnancie

Journal of Family and Reproductive Health, 2008
Objective:To investigate the hematologic indices of mothers in non-immune hydrops fetalis pregnancies and identify the possible causative role of Alpha-Thalassemia among them.
Saeed Reza Ghaffari, Farzaneh Larti, Tayebeh Sabokbar, Maryam Rafati, Jila Dastan, Laleh Eslamian, Fatemeh Rahimi, Sedighe Borna   +7 more
doaj  

The impact of in utero transfusions on perinatal outcomes in patients with alpha thalassemia major: the UCSF registry. [PDF]

Blood Adv, 2023
Schwab ME, Lianoglou BR, Gano D, Gonzalez Velez J, Allen IE, Arvon R, Baschat A, Bianchi DW, Bitanga M, Bourguignon A, Brown RN, Chen B, Chien M, Davis-Nelson S, de Laat MWM, Ekwattanakit S, Gollin Y, Hirata G, Jelin A, Jolley J, Meyer P, Miller J, Norton ME, Ogasawara KK, Panchalee T, Schindewolf E, Shaw SW, Stumbaugh T, Thompson AA, Towner D, Tsai PS, Viprakasit V, Volanakis E, Zhang L, Vichinsky E, MacKenzie TC.   +35 more
europepmc   +1 more source

Machine learning improves detection of alpha thalassemia carriers compared to clinical features. [PDF]

Sci Rep
Mohammadi E, Rastegar M, Jamshidnezhad A, Azizi A.   +3 more
europepmc   +1 more source