Results 11 to 20 of about 1,319,935 (211)
Alpha thalassemia genotypes in Kuwait [PDF]
BMC Medical Genetics, 2020 Background The frequency of the alpha thalassemia trait is approximately 40% in the Kuwaiti population, but there has been no comprehensive study of the prevalent alleles.
Adekunle Adekile +4 more
doaj +6 more sources
Screening of Some Indicators for Alpha-Thalassemia in Fujian Province of Southern China [PDF]
International Journal of General Medicine, 2021 Lin Zheng, Hailong Huang, Xiaoqing Wu, Linjuan Su, Qingmei Shen, Meiying Wang, Na Lin, Liangpu Xu Medical Genetic Diagnosis and Therapy Center of Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fujian Key ...
Zheng L +7 more
doaj +3 more sources
EJHaem, 2021 The genotype and phenotype correlation between coinheritance of heterozygous beta‐thalassemia with the alpha‐globin triplication is unclear. In this study we have investigated and reviewed alpha triplication frequency in beta‐thalassemia carriers, sickle
Mohammad Hamid +2 more
exaly +3 more sources
A comprehensive case study of deep learning on the detection of alpha thalassemia and beta thalassemia using public and private datasets [PDF]
Scientific ReportsThis study explores the performance of deep learning models, specifically Convolutional Neural Networks (CNN) and XGBoost, in predicting alpha and beta thalassemia using both public and private datasets.
Muhammad Umar Nasir +7 more
doaj +3 more sources
Alpha‐thalassemia. Case report alpha‐thalassemia in a Costa Rican family, A case report [PDF]
Clinical Case Reports, 2021 This case report highlights the importance for health care providers to be aware of the αlpha‐thalassemia syndromes, their relevance to clinical care and family counseling, appropriate diagnostic algorithm for definitive diagnosis.
Mariela Solano‐Vargas +2 more
doaj +7 more sources
Genetics in Medicine, 2011 Alpha thalassemia major (ATM) is inherited in an autosomal recessive manner. This means that two non-functioning genes have to be passed to the fetus from each parent, resulting in loss of function of all four alpha globin genes in the fetus. A pregnancy
Renzo Galanello, A Cao
exaly +4 more sources
Revista Brasileira De Hematologia E Hemoterapia, 2015 BACKGROUND: In sickle cell disease, the quantification of Hb A2 is important for the differential diagnosis between sickle cell anemia (Hb SS) and Hb S/ß0-thalassemia.OBJECTIVE: To determine Hb A2 levels as quantified by high performance liquid ...
Marilda Souza Gonçalves, Ney Boa-Sorte
exaly +4 more sources
An analysis of the distribution and spectrum of alpha thalassemia mutations in Rasht City, North of Iran [PDF]
Frontiers in Pediatrics, 2023 BackgroundAlpha thalassemia is one of the most common hereditary hemoglobin disorders worldwide, particularly in the Middle East, including Iran.
Mona Asghari Ahmadabad +8 more
doaj +2 more sources
Clinical Utility of the Addition of Molecular Genetic Testing to Newborn Screening for Hemoglobinopathies for Confirmation of Alpha-Thalassemia Trait [PDF]
International Journal of Neonatal ScreeningHemoglobinopathies are commonly detected by newborn screening (NBS). One of the most difficult to accurately diagnose is alpha-thalassemia, which is indicated by the presence of hemoglobin (Hb) Barts on NBS.
Lisa M. Shook +2 more
doaj +2 more sources
Hematological analysis of alpha-thalassemia: A single-center, retrospective clinical study. [PDF]
PLoS ONEObjectivesTo determine the optimal cutoffs of the three indicators (MCV, MCH and HbA2) for alpha-thalassemia screening and to evaluate the validity of these indicators in Fujian Province, China.MethodsWe conducted a retrospective analysis on the results ...
Lin Zheng +7 more
doaj +2 more sources