Results 21 to 30 of about 1,319,935 (211)
Genetic Analysis of Alpha-Thalassemia Mutations in Thi-Gar Province, Iraq [PDF]
Archives of Razi Institute, 2022 The prevalence of alpha-thalassemia as a major health problem in the south of Iraq has highlighted the necessity of investigations and screening of patients with thalassemia.
A. H Odah Al-Musawi +2 more
doaj +2 more sources
Deletional Alpha-Thalassemia Alleles in Amazon Blood Donors
Advances in Hematology, 2020 Alpha-thalassemia is highly prevalent in the plural society of Brazil and is a public health problem. There is limited knowledge on its accurate frequency and distribution in the Amazon region.
Fernanda Cozendey Anselmo +7 more
doaj +2 more sources
Turkish Journal of Hematology, 2015 INTRODUCTION: Alpha thalassemia syndromes are caused by mutations on one or more of the four α-globin genes. Mutations could be either more commonly deletional or non-deletional. As some deletions (3.7 and 4.2) cause α+-thalassemia, some cause (
Zeynep Karakaş +11 more
doaj +2 more sources
Third-generation sequencing identified a novel complex variant in a patient with rare alpha-thalassemia [PDF]
BMC PediatricsBackground Thalassemias represent some of the most common monogenic diseases worldwide and are caused by variations in human hemoglobin genes which disrupt the balance of synthesis between the alpha and beta globin chains.
Cong Zhou +5 more
doaj +2 more sources
Alpha thalassemia and alpha-MRE haplotypes in Uruguayan patients with microcytosis and hypochromia without anemia [PDF]
Genetics and Molecular Biology, 2021 Alpha thalassemia is the most common genetic disorder across the world, being the α-3.7 deletion the most frequent mutation. In order to analyze the spectrum and origin of alpha thalassemia mutations in Uruguay, we obtained a sample of 168 unrelated ...
Ana María Soler +7 more
doaj +1 more source
Molecular and Haematological Characteristics of alpha-Thalassemia Deletions in Yogyakarta Special Region, Indonesia. [PDF]
Rep Biochem Mol Biol, 2021 Background alpha-Thalassemia is caused primarily by deletions of one to two alpha-globin genes and is characterized by absent or deficient production of alpha-globin protein.
Husna N, Handayani NSN.
europepmc +2 more sources
Molecular Detection of Alpha Thalassemia: A Review of Prevalent Techniques. [PDF]
Medeni Med J, 2021 Alpha thalassemia (α-thalassemia) is an autosomal recessive disorder due to the reduction or absence of α globin chain production. Laboratory diagnosis of α-thalassemia requires molecular analysis for the confirmatory diagnosis.
Vijian D +4 more
europepmc +2 more sources
Association between Alpha-Thalassemia Carrier Prevalence and Incidence of COVID-19
Journal of Preventive, Diagnostic and Treatment Strategies in Medicine, 2022 BACKGROUND: The association between COVID-19 incidence and genetic underlying is an interesting issue. The possible association between thalassemia and COVID-19 is proposed.
Pathum Sookaromdee, Viroj Wiwanitkit
doaj +1 more source
Mediterranean Journal of Hematology and Infectious Diseases, 2022 Background Sickle cell disease is a protean disease with limited data on Nigeria’s phenotypic and genetic variants. This study was conducted to provide baseline data on these variants by characterising the existing forms of sickle cell disease and ...
F. Fasola +5 more
semanticscholar +1 more source
Journal of clinical laboratory analysis (Print), 2021 Stroke is a devastating complication of sickle cell anemia (SCA) and can be predicted through abnormally high cerebral blood flow velocity using transcranial Doppler Ultrasonography (TCD).
O. Ojewunmi +5 more
semanticscholar +1 more source