Results 61 to 70 of about 38,874 (189)

Recent Insights Into Circulating Adipokines in Obesity: Systematic Review and Meta‐Analysis

Obesity Science &Practice, Volume 12, Issue 1, February 2026.
ABSTRACT Background Adipokines are dysregulated in obesity and exacerbate proinflammatory conditions. Although several studies have investigated adipokine levels in obesity, their findings have been inconsistent, leaving the precise nature of these alterations uncertain.
Sunita Sunita, Mohammad Ghozali, Mohammad Rizki Akbar, Annisa Dewi Nugrahani, Iis Inayati Rakhmat, Siti Nur Fatimah, Yuni Susanti Pratiwi, Eko Fuji Ariyanto, Gaga Irawan Nugraha, Mas Rizky A. A. Syamsunarno, Tri Hanggono Achmad   +10 more
wiley   +1 more source

Novel deletions and unusual genetic mechanisms underlying alpha-thalassemia [PDF]

, 2016
Hemoglobin (Hb) is a protein responsible for oxygen transportation from lungs to the entire body. It is composed by four globular subunits - the globins - each with a central core containing a heme molecule.
Batalha-Reis, Ana, Coelho, Andreia, Faustino, Paula, Ferrão, José, Forjaz-Lacera, João, Gomes, Susana, Gonçalves, João, Gonçalves, Lúcia, Kjollerstrom, Paula, Lavinha, João, Maia, Raquel, Miranda, Armandina, Pina, Francisca, Seuanes, Filomena, Silva, Marisa, Sonesson, A., Valtonen-Andrá, C.   +16 more
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International Multidisciplinary Consensus Report on Definitions, Diagnostic Criteria, and Management of Fatty Pancreas: A Joint Statement Endorsed by EPC, APA, EASD, EASL, ESGAR, ESGE, ESP, ESPCG, ESPEN, ESPGHAN, IAP, JPS, KPBA, LAPSG, and UEG

United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT This international, multidisciplinary consensus report represents the first effort to systematically define and characterize fatty pancreas. A key outcome of this endeavor was the recommendation to adopt “fatty pancreas” as the standardized and inclusive term to describe all forms of fat accumulation in the pancreas.
Miroslav Vujasinovic, Ihsan Ekin Demir, Giovanni Marchegiani, Peter Hegyi, Livia Archibugi, Roberto Valente, Gabriele Capurso, Heiko Witt, Stefanos Bonovas, Daniele Piovani, Jonas Rosendahl, Patrick Maisonneuve, Caroline S. Verbeke, Muşturay Karçaaltıncaba, J. Enrique Dominguez‐Muñoz, Isabelle Scheers, Laszlo Czako, Robert Wagner, Vinciane Rebours, Daniel Öhlund, Ilkay S. Idilman, Kasper Overbeek, Natalya Gubergrits, Trond Engjom, Albrecht Neesse, Minoti Apte, Mihailo Bezmarević, Rickmer Braren, Stefania Bunduc, Güralp Onur Ceyhan, Manil Dinesh Chouhan, Anne Couvelard, Jérôme Cros, Daniel de la Iglesia, Enrique de‐Madaria, Joost P. H. Drenth, Asbjørn Mohr Drewes, Arantza Fariña Sarasqueta, Pierluigi Fracasso, Sven Francque, Jens Brøndum Frøkjær, Julio Iglesias‐Garcia, Pramod Garg, Felicia Gerst, Antanas Gulbinas, Ibrahim Halil Gürcinar, Martin Heni, Jong Jin Hyun, Eduard Jonas, Mariia Kiriukova, Masayuki Kitano, Aleksander Krag, Johanna Laukkarinen, Mónika Lipp, Martin Lovecek, Marc Martignoni, Etna Masip, Ryotaro Matsumoto, Anders Molven, Tetiana Mozhyna, Lenka Nosakova, Verena Obmann, Johann Ockenga, Sanjay Pandanaboyana, Nikola Panić, Georgios Papachristou, Analia Verónica Pasqua, Katarzyna M. Pawlak, Mario Pelaez‐Luna, Ivonne Regel, Sara Regnér, Stuart Robinson, Andrada Seicean, Vijay Singh, Mark M. Smits, Min Je Sung, Matteo Tacelli, Roy Taylor, Brigitta Teutsch, Mihaela Udrescu, Michael Wilschanski, Aslihan Yavas, Giulia A. Zamboni, J. Matthias Löhr   +83 more
wiley   +1 more source

Does vitamin E have a role in treatment and prevention of anemia? [PDF]

, 2011
Vitamin E is a highly effective fat-soluble vitamin with a variety of cellular membrane stabilizing-antioxidant and non-antioxidant functions. Vitamin E has been suggested to prevent the oxidation of polyunsaturated fatty acids in red blood cell (RBC ...
Iqbal, Mohammad Perwaiz, Jilani, Tanveer
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Is Ferroptosis the Mechanistic Bridge Connecting Iron Dysregulation to Muscle Wasting and Functional Decline in Aging?

Aging Cell, Volume 25, Issue 2, February 2026.
This work proposes ferroptosis as a mechanistic driver of age‐related muscle dysfunction, whereby iron dyshomeostasis and impaired antioxidant capacity promote lipid peroxidation, and eventually trigger ferroptosis, leading to muscle wasting, and ultimately contributing to weakness and functional decline with aging.
Rola S. Zeidan, Simon Reinhard, Anna Picca, Emanuele Marzetti, Christiaan Leeuwenburgh, James F. Collins, Stephen D. Anton   +6 more
wiley   +1 more source

Prevalence of Severe Thalassemia and Performance of Prenatal Screening Tests Among Pregnant Women at Siriraj Thalassemia Center in Thailand

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Severe thalassemia remains a significant public health concern in Southeast Asia. Prenatal screening is an effective strategy for early detection and prevention. This study aimed to determine the prevalence of severe thalassemia and assess the performance of prenatal screening at the Siriraj Thalassemia Center, Siriraj Hospital, Thailand.
Kwandao Malasai, Usa Chaikledkaew, Pattarawalai Talungchit, Sitaporn Youngkong, Wanvisa Udomsinprasert, Chanin Limwongse, Jiraphun Jittikoon   +6 more
wiley   +1 more source

Basiliximab in the Prophylaxis of aGVHD for Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Thalassemia Major: A Prospective, Multicenter, Open‐Label, Randomized Controlled Study

American Journal of Hematology, Volume 101, Issue 3, Page 628-632, March 2026.
Zhenbin Wei, Rongrong Liu, Lingling Shi, Qiaochuan Li, Lianjin Liu, Baoshi Zheng, Chunjie Qin, Hong Chen, Guyun Wang, Meiqing Wu, Gaohui Yang, Ruolin Li, Zhaoping Gan, Qi Zhou, Jing Fan, Xuemei Zhou, Yinghua Chen, Zhiyu Zeng, Zhongming Zhang, Yongrong Lai   +19 more
wiley   +1 more source

Receptor‐Dependent and ‐Independent Effects of Hemin on Platelet Plasma Membrane Disintegration

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Microhemorrhages lead to the release of erythrocytes, which are then degraded and lysed. These hemolyses result in the liberation of free iron‐containing hemin. Hemin induces platelet activation and ferroptosis. Inhibition of GPVI/CLEC‐2 receptor‐mediated ITAM‐signaling inhibits hemin‐induced platelet activation (low hemin concentrations). Deferoxamine,
Zoi Laspa, Anne‐Katrin Rohlfing, Ravi Hochuli, Pamela Weronika Sowa, Tatsiana Castor, Meinrad Paul Gawaz   +5 more
wiley   +1 more source

Studies of bone mineral density in children affected by dietary intolerances [PDF]

, 2014
The Pediatric Department of the University of Ferrara has developed a special expertise in the field of hemoglobinopathies and has also an interest in gastrointestinal diseases.
Baldan, Alessandro, Ballardini, Elisa, Borgna-Pignatti, Caterina, Malaventura, Cristina   +3 more
core   +1 more source

شيوع هموگلوبينوپاتی با توجه به ميزان انواع هموگلوبين و ارتباط آنها با حجم متوسط گلبول قرمز در بين دانش آموزان پيش‌دانشگاهی شهر بوشهر؛ 1386 [PDF]

, 2009
زمينه: هموگلوبينوپاتی ها از جمله تالاسمی و کم‎خونی داسی شکل از فراوان ترين اختلالات ژنتيکی در انسان می باشند. اين بيماری ها در حالت هتروزيگوت بدون علائم بالينی بوده ولی در حالت هموزيگوت نياز به خون و مراقبت های بيمارستانی دارند.
خمیسی پور, غلامرضا, عبیدی, نرگس, موحد, علی   +2 more
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