Results 91 to 100 of about 13,277 (199)

A genus-specific nsp12 region impacts polymerase assembly in Alphacoronavirus and Gammacoronavirus. [PDF]

J Biol Chem
Coronavirus relevancy for human health has surged over the past 20 years as they have a propensity for spillover into humans from animal reservoirs resulting in pandemics such as COVID-19. The diversity within the Coronavirinae subfamily and high infection frequency in animal species worldwide creates a looming threat that calls for research across all
Hoferle PJ, Anderson TK, Kirchdoerfer RN.   +2 more
europepmc   +3 more sources

Candidates in Astroviruses, Seadornaviruses, Cytorhabdoviruses and Coronaviruses for +1 frame overlapping genes accessed by leaky scanning [PDF]

, 2010
Background Overlapping genes are common in RNA viruses where they serve as a mechanism to optimize the coding potential of compact genomes. However, annotation of overlapping genes can be difficult using conventional gene-finding software.
Andrew E Firth, John F Atkins, AE Firth, AE Firth, BYW Chung, AE Firth, AE Firth, E Balmori Melian, R Belshaw, B Jiang, MM Willcocks, C Touriol, SR Finkbeiner, HC Zhu, R Rivera, A Kapoor, SS Monroe, SA Sedman, M Kozak, TL Lewis, U Geigenmüller, H Attoui, H Attoui, H Attoui, F Mohd Jaafar, D Matsuda, H Attoui, T Wetzel, RG Dietzgen, F Heim, JN Barr, CP Joshi, IK Jordan, C Rancurel, AE Gorbalenya, AO Pasternak, SD Senanayake, PC Woo, BQ Dong, ML Powell, DK Chu, SF Altschul, MA Larkin, P Rice   +43 more
core   +2 more sources

A Narrative Review on the Recent Insights Into the Pathogenicity and Potential Role of Middle East Respiratory Syndrome Coronavirus (MERS‐CoV) in the Emergence of “Disease X”

Health Science Reports, Volume 8, Issue 10, October 2025.
ABSTRACT Background and Aims Following the end of the COVID‐19 global emergency, concern has shifted to “Disease X,” a hypothetical, highly transmissible, and deadly pathogen, and Middle East Respiratory Syndrome Coronavirus (MERS‐CoV) is a prime candidate for this. This review explores its epidemiology, mutations, transmission, and potential to become
Zubaier Ahmed, Kazi Milenur Rahman Prattay, Sabrina Sharmin, Fatema‐Tuz‐Zohora, Asef Raj, Forhad Bin Faruk, Bagdad Ahmed, Humair Bin Md Omer, Anika Awal Omi, Fazle Rabbi, Nasiba Binte Bahar, Sumiya Sharmin Mou, Mehedi Islam, Eshaba Karim, Md. Elias Al‐Mamun   +14 more
wiley   +1 more source

Effects of SADS‐CoV accessory proteins NS3a, NS7a, and NS7b on viral pathogenicity: A multi‐omics investigation

iMetaOmics, Volume 2, Issue 3, September 2025.
This study has elucidated the role of three swine acute diarrhea syndrome coronavirus (SADS‐CoV) accessory proteins in influencing viral pathogenicity and preliminarily explored the host molecular targets and pathways affected by the NS3a, NS7a, and NS7b proteins of SADS‐CoV.
Xiaoling Yan, Xiaoli Zhang, Ling Zhou, Xiaoya Zhao, Qianniu Li, Tian Lan, Jun Fu, Jingyun Ma   +7 more
wiley   +1 more source

Identification of a novel bat papillomavirus by metagenomics [PDF]

, 2012
published_or_final_versio
Ho, CC, Lau, SKP, Leung, ASP, Tsang, KL, Tse, H, Tsoi, HW, Woo, PCY, Yuen, KY   +7 more
core   +1 more source

Understanding the Enigmatic Dance of Immune‐Mediated Viral Infections and Their Pathogenetic Mechanisms

Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.
This graphical representation illustrates the multifaceted nature of the immune response in viral infections, demonstrating both its protective and potentially harmful aspects. While a properly regulated immune reaction facilitates viral clearance and promotes general recovery, an overly robust or misdirected response—exemplified by Type III or Type IV
Muhammed Cesim Karabulut, Tuba Çiğdem Oğuzoğlu   +1 more
wiley   +1 more source

Bactericidal, Virucidal, and Biocompatible Properties of 3D Printed Materials Enhanced with Copper and Zinc Nanoparticles

Global Challenges, Volume 9, Issue 8, August 2025.
As population growth, urbanization, and climate change increase the spread of pathogens, hospital infections now affect 1 in 31 patients, costing billions annually. This study presents a new approach by integrating copper and zinc oxide nanoparticles into 3D‐printed materials.
Andrei‐Florin Sandu, Lauren Acton, Phillip Gould   +2 more
wiley   +1 more source

Detection of novel coronaviruses from dusky fruit bat (Penthetor lucasi) in Sarawak, Malaysian Borneo

Veterinary Medicine and Science, 2023
Background Sarawak has one of the highest diversity of fruit bats species (family Pteropodidae) in Malaysia, with 19 species described. Most coronavirus (CoV) studies have mainly focused on insectivorous bats, resulting in a lack of information on CoVs ...
Sultana Parvin Habeebur‐Rahman, Vaenessa Noni, Faisal Ali Anwarali Khan, Cheng‐Siang Tan   +3 more
doaj   +1 more source

Identification of an enterovirus recombinant with a torovirus-like gene insertion during a diarrhea outbreak in fattening pigs [PDF]

, 2017
Diarrhea outbreaks in pig farms have raised major concerns in Europe and USA, as they can lead to dramatic pig losses. During a suspected outbreak in Belgium of porcine epidemic diarrhea virus (PEDV), we performed viral metagenomics to assess other ...
Carpentier, Sebastien, Christiaens, Isaura, Conceição-Neto, Nádia, Cui, Tingting, Heylen, Elisabeth, Matthijnssens, Jelle, Nauwynck, Hans, Theuns, Sebastiaan, Van Ranst, Marc, Yinda, Claude Kwe, Zeller, Mark   +10 more
core   +2 more sources

A novel genotyping system based on site polymorphism on spike gene reveals the evolutionary pathway of porcine epidemic diarrhea virus

iMetaOmics, Volume 2, Issue 2, June 2025.
This study focuses on porcine epidemic diarrhea virus (PEDV), a highly virulent and rapidly evolving coronavirus threatening global swine production. We established a novel genotype system of PEDV targeting site‐specific polymorphisms in the spike (S) protein.
Mingkai Lei, Huimin Li, Xiaoyu Chen, Xiaozhen Li, Xuexiang Yu, Shengnan Ruan, Hao Wu, Ahmed H. Ghonaim, Ziyang Yan, Wentao Li, Qigai He   +10 more
wiley   +1 more source