Results 91 to 100 of about 11,673 (180)
Sequence alignment of homologous CoV RBD.
, 2012 Alignment was carried out with the T-Coffee program (http://www.ebi.ac.uk/). RBD sequences of TGEV, canine and feline CoVs (Alphacoronavirus 1), human CoVs (Alphacoronavirus), Bulbul-CoV (putative Deltacoronavirus) and IBV (Gammacoronavirus). Sequence of
César Santiago (146919) +5 more
core +1 more source
Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.Background Young pigs are often coinfected with porcine circovirus 2 (PCV2) and porcine epidemic diarrhea virus (PEDV). This study aimed to determine the impact of coinfection of pigs with PCV2 and PEDV. Forty 16‐day‐old crossbred mixed‐sex piglets were assigned to four groups (n = 10/group, NEG‐CONTROL, PCV2‐CONTROL, PCV2+PEDV, and PEDV‐CONTROL).
Priscilla F. Gerber +7 more
wiley +1 more source
Veterinary Medicine and Science, 2023 Background Sarawak has one of the highest diversity of fruit bats species (family Pteropodidae) in Malaysia, with 19 species described. Most coronavirus (CoV) studies have mainly focused on insectivorous bats, resulting in a lack of information on CoVs ...
Sultana Parvin Habeebur‐Rahman +3 more
doaj +1 more source
Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.Porcine epidemic diarrhea virus (PEDV), an enteropathogenic coronavirus causing high mortality in neonatal piglets, continues to threaten global swine industries. Frequent mutations in the spike (S) protein of PEDV, particularly in emerging variants, have substantially compromised commercial vaccine efficacy.
Yang-Yang Li +8 more
wiley +1 more source
, 2022 BackgroundHuman coronaviruses (HCoVs) are associated with upper respiratory tract infections. Although studies have analyzed the clinical and epidemiological characteristics of HCoV-associated infections, no multi-center studies have been conducted in ...
Soo-Han Choi (4030835) +6 more
core +1 more source
The Tetrahydroisoquinoline Derivative SP9 Exhibits Antiviral Activity Against PEDV and MHV
Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.Coronaviruses exhibit high mutation rates and cross‐species transmissibility, posing a persistent threat to human and animal health and underscoring the urgent need for antivirals that can compensate for the limited crossprotection afforded by current vaccines.
Junhai Zhu +7 more
wiley +1 more source
Spike-based phylogenetically defined clades within the Alphacoronavirus 1 species [PDF]
, 2017 Abstract Taxonomic classification for the Coronaviridae can be challenging, due to the wide host tropism and highly variable genome of the viruses in this Family.
Whittaker, Gary R. +2 more
openaire +1 more source
A New Bat-HKU2–like Coronavirus in Swine, China, 2017
Emerging Infectious Diseases, 2017 We identified from suckling piglets with diarrhea in China a new bat-HKU2–like porcine coronavirus (porcine enteric alphacoronavirus). The GDS04 strain of this coronavirus shares high aa identities (>90%) with the reported bat-HKU2 strains in ...
Lang Gong +8 more
doaj +1 more source
Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.Swine acute diarrhea syndrome coronavirus (SADS‐CoV) is an emerging enteric coronavirus that causes severe diarrhea and high mortality in neonatal piglets. Its broad host range, tropism for human‐origin cells, and limited vaccine availability underscore the importance of defining viral determinants of pathogenicity.
Nian-Qi Zhang +11 more
wiley +1 more source
An alphacoronavirus polymerase structure reveals conserved replication factor functions
Nucleic Acids ResearchAbstract Coronaviruses are a diverse subfamily of viruses containing pathogens of humans and animals. This subfamily of viruses replicates their RNA genomes using a core polymerase complex composed of viral non-structural proteins: nsp7, nsp8 and nsp12.
Thomas K Anderson +5 more
openaire +2 more sources