Potent neutralising monoclonal antibodies targeting the spike of NL63 coronavirus [PDF]
NL63 is an alphacoronavirus that uses the same ACE2 receptor as SARS-CoV and SARS-CoV-2, but generally causes mild respiratory illness. In a cohort of healthy adults, we characterised humoral responses against NL63 spike and isolated a panel of human ...
Wen Shi Lee +21 more
doaj +2 more sources
Coding-complete genome sequence of an <i>Alphacoronavirus</i> isolated in <i>Rattus norvegicus</i> captured in an urban park in France. [PDF]
Beissat K +7 more
europepmc +2 more sources
Complete Genome Sequence of an Alphacoronavirus from Common Vampire Bats in Peru
Bats host diverse coronaviruses, including taxa capable of pandemic spread in humans. We report the genome of an alphacoronavirus from a neotropical bat species ( Desmodus rotundus ) in Peru, which contributes to our understanding of bat coronaviruses in nature.
Laura M. Bergner +2 more
+6 more sources
Aberrant Cholesterol Metabolic Genes Regulation in a Negative Feedback Loop Induced by an Alphacoronavirus [PDF]
Porcine epidemic diarrhea virus (PEDV) is an alphacoronavirus that causes acute inflammation and severe diarrhea in newborn piglets with a high mortality rate. Given that cholesterol is required for coronavirus infection in vitro, the role of endogenous cholesterol metabolism in regulating coronavirus infection and the mechanism behind it ought to be ...
Haoyu Liu +5 more
openalex +4 more sources
Structural and Biological Basis of Alphacoronavirus nsp1 Associated with Host Proliferation and Immune Evasion [PDF]
Non-structural protein 1 (nsp1) is only characterized in alphacoronaviruses (α-CoVs) and betacoronaviruses (β-CoVs). There have been extensive researches on how the β-CoVs nsp1 regulates viral virulence by inhibiting host protein synthesis, but the regulatory mechanism of the α-CoVs nsp1 is still unclear.
Zhou Shen +6 more
openalex +5 more sources
Erratum to: Alphacoronavirus in urban Molossidae and Phyllostomidae bats, Brazil [PDF]
© 2016 The Author(s). Open Access This artic International License (http://creativecommons reproduction in any medium, provided you g the Creative Commons license, and indicate if (http://creativecommons.org/publicdomain/ze • We accept pre-submission inquiries • Our selector tool helps you to find the most relevant journal • We provide round the clock ...
Karen Miyuki Asano +6 more
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Dispersal history of Miniopterus fuliginosus bats and their associated viruses in east Asia.
In this study, we examined the role of the eastern bent-winged bat (Miniopterus fuliginosus) in the dispersion of bat adenovirus and bat alphacoronavirus in east Asia, considering their gene flows and divergence times (based on deep-sequencing data ...
Thachawech Kimprasit +21 more
doaj +1 more source
Seasonality of Common Human Coronaviruses, United States, 2014–2021
The 4 common types of human coronaviruses (HCoVs)—2 alpha (HCoV-NL63 and HCoV-229E) and 2 beta (HCoV-HKU1 and HCoV-OC43)—generally cause mild upper respiratory illness.
Melisa M. Shah +5 more
doaj +1 more source

