Results 51 to 60 of about 10,817 (123)

Scientific Opinion on porcine epidemic diarrhoea and emerging porcine deltacoronavirus

EFSA Journal, 2014
In the last decade, many porcine epidemic diarrhoea (PED) outbreaks have been reported by several countries in Asia whereas only a few Member States of the European Union (EU) have reported PED clinical cases and/or PED virus (PEDV)‐seropositive animals.
EFSA Panel on Animal Health and Welfare (AHAW)
doaj   +1 more source

Concomitant Infection With Porcine circovirus 2 and Porcine Epidemic Diarrhea Virus Does Not Increase Enteritis Severity in Experimentally Infected Weaned Piglets

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Background Young pigs are often coinfected with porcine circovirus 2 (PCV2) and porcine epidemic diarrhea virus (PEDV). This study aimed to determine the impact of coinfection of pigs with PCV2 and PEDV. Forty 16‐day‐old crossbred mixed‐sex piglets were assigned to four groups (n = 10/group, NEG‐CONTROL, PCV2‐CONTROL, PCV2+PEDV, and PEDV‐CONTROL).
Priscilla F. Gerber, Jianqiang Zhang, Andrew Noel, Bin Wang, Yaowei Huang, Patrick G. Halbur, Tanja Opriessnig, Jizong Li   +7 more
wiley   +1 more source

Development and characterization of segment-specific enteroids from the pig small intestine in Matrigel and transwell inserts: insights into susceptibility to porcine epidemic diarrhea Virus

Frontiers in Immunology
IntroductionThe critical early stages of infection and innate immune responses to porcine epidemic diarrhea virus (PEDV) at the intestinal epithelium remain underexplored due to the limitations of traditional cell culture and animal models.
Lu Yen, Rahul K. Nelli, Ning-Chieh Twu, Juan Carlos Mora-Díaz, Gino Castillo, Panchan Sitthicharoenchai, Luis G. Giménez-Lirola   +6 more
doaj   +1 more source

Emergence of a Highly Virulent Porcine Epidemic Diarrhea Virus (PEDV) G2c Subtype in China: Isolation, Genetic and Pathogenic Characterization, and Cross‐Neutralizing Antibody Response

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine epidemic diarrhea virus (PEDV), an enteropathogenic coronavirus causing high mortality in neonatal piglets, continues to threaten global swine industries. Frequent mutations in the spike (S) protein of PEDV, particularly in emerging variants, have substantially compromised commercial vaccine efficacy.
Yang-Yang Li, Chuan-Hao Fan, Hai-Xia Li, Hui-Qiang Zhen, Ye-Qing Zhu, Shouyu Wang, Bin Wang, Yao-Wei Huang, Linzhu Ren   +8 more
wiley   +1 more source

Detection of novel coronaviruses from dusky fruit bat (Penthetor lucasi) in Sarawak, Malaysian Borneo

Veterinary Medicine and Science, 2023
Background Sarawak has one of the highest diversity of fruit bats species (family Pteropodidae) in Malaysia, with 19 species described. Most coronavirus (CoV) studies have mainly focused on insectivorous bats, resulting in a lack of information on CoVs ...
Sultana Parvin Habeebur‐Rahman, Vaenessa Noni, Faisal Ali Anwarali Khan, Cheng‐Siang Tan   +3 more
doaj   +1 more source

The Tetrahydroisoquinoline Derivative SP9 Exhibits Antiviral Activity Against PEDV and MHV

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Coronaviruses exhibit high mutation rates and cross‐species transmissibility, posing a persistent threat to human and animal health and underscoring the urgent need for antivirals that can compensate for the limited crossprotection afforded by current vaccines.
Junhai Zhu, Yuting Jiang, Kaifang Yang, Fei Gao, Wenbao Qi, Lihong Huang, Yue Wang, Bin Li   +7 more
wiley   +1 more source

Prevention of Porcine Epidemic Diarrhea Virus With Nanotube‐Adjuvanted Oral DNA Vaccines

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine epidemic diarrhea virus (PEDV) causes severe diarrhea in piglets. The ideal route of protection against PEDV for piglets is through passive (lactogenic) immunity, which is not provided by current inactivated and subunit vaccines on the market. In this study, we investigated whether a DNA vaccine encoding the full PEDV spike protein adjuvanted ...
Hsing-Chieh Wu, Thu-Dung Doan, Wan-Chen Chang, Min-Kung Hsu, Hsian-Yu Wang, Jiahorng Liaw, Chia-Jung Chang, Chun-Yen Chu, Nan-Hua Chen   +8 more
wiley   +1 more source

A New Bat-HKU2–like Coronavirus in Swine, China, 2017

Emerging Infectious Diseases, 2017
We identified from suckling piglets with diarrhea in China a new bat-HKU2–like porcine coronavirus (porcine enteric alphacoronavirus). The GDS04 strain of this coronavirus shares high aa identities (>90%) with the reported bat-HKU2 strains in ...
Lang Gong, Jie Li, Qingfeng Zhou, Zhichao Xu, Li Chen, Yun Zhang, Chunyi Xue, Zhifen Wen, Yongchang Cao   +8 more
doaj   +1 more source

Celastrol Suppresses Porcine Deltacoronavirus Replication by Modulating Endoplasmic Reticulum Stress‐Associated Ca2+ Balance

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine deltacoronavirus (PDCoV) infection causes watery diarrhea and even death in neonatal piglets, leading to substantial economic losses. Meanwhile, emerging evidence indicates the potential risk of PDCoV to threaten human health and public safety. However, the effective vaccines or medicines are deficient.
Jialu Zhang, Yuqian Liu, Letao Gao, Wenzhe Liu, Ru Yan, Die Zhu, Zhouyuan Wang, Lianci Peng, Rendong Fang, Tingting Chen, Bin Li   +10 more
wiley   +1 more source

Whole‐Genome Characterization of Rodent Coronaviruses (RCoVs) in Thailand, 2024–2025

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Rodents are recognized as important reservoirs of coronaviruses, contributing to viral diversity and potential zoonotic emergence. However, data on rodent coronaviruses (RCoVs) in Thailand remained limited. This study aimed to determine the prevalence, genetic characteristics, and phylogenetic relationships of RCoVs circulating in rodent populations ...
Chanakarn Nasamran, Supassama Chaiyawong, Supanat Boonyapisitsopa, Napawan Bunpapong, Kamonpan Charoenkul, Alongkorn Amonsin, Xing-Lou Yang   +6 more
wiley   +1 more source