Results 61 to 70 of about 10,817 (123)

The PCK2‐Traf6‐Tollip Axis Restricts PEDV Replication by Orchestrating Selective Autophagic Degradation of the Viral Nucleocapsid Protein

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine epidemic diarrhea virus (PEDV) is a devastating enteric pathogen in neonatal piglets, causing outbreaks with high mortality. The lack of effective vaccines or treatments makes elucidating host‐pathogen interactions essential for developing control strategies.
Ao Gao, Xinyu Yang, Wenzhen Qin, Dongfang Zheng, Yuchang Liu, He Sun, Zongyan Chen, Guangzhi Tong, Shuang Xue, Ning Kong, Lanlan Zheng, Bin Li   +11 more
wiley   +1 more source

Characteristics of Avian Coronaviruses in China From 2020 to 2023

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Avian coronaviruses (CoVs) represent a significant threat to the poultry industry. To understand the epidemiological characteristics of avian CoVs in China, a nationwide surveillance was performed across 16 provinces from 2020 to 2023. More than 46,000 oropharyngeal/cloacal swab samples were collected and detected by RT‐PCR using specific primers for ...
Suchun Wang, Jinyu Sui, Junhui Pan, Shimeng Wei, Qian Qi, Chao Li, Xiyue Zhang, Kaicheng Wang, Guozhong Zhang   +8 more
wiley   +1 more source

Receptor-binding loops in alphacoronavirus adaptation and evolution

Nature Communications, 2017
Coronaviruses have a relatively high mutation rate, potentially allowing fast adaptation to changing pressures. Here, Wong et al. provide the structure of the receptor-binding domain (RBD) of the human coronavirus HCoV-229E and its receptor and analyze ...
Alan H. M. Wong, Aidan C. A. Tomlinson, Dongxia Zhou, Malathy Satkunarajah, Kevin Chen, Chetna Sharon, Marc Desforges, Pierre J. Talbot, James M. Rini   +8 more
doaj   +1 more source

Determination of Ferret Enteric Coronavirus Genome in Laboratory Ferrets

Emerging Infectious Diseases, 2017
Ferret enteric coronavirus (FRECV) RNA was detected in laboratory ferrets. Analysis of the complete genome sequence of 2 strains, FRCoV4370 and FRCoV063, revealed that FRECV shared 49.9%–68.9% nucleotide sequence identity with known coronaviruses.
Tian-Cheng Li, Sayaka Yoshizaki, Michiyo Kataoka, Yen Hai Doan, Yasushi Ami, Yuriko Suzaki, Tomofumi Nakamura, Naokazu Takeda, Takaji Wakita   +8 more
doaj   +1 more source

Detection of alpha- and betacoronaviruses in rodents from Yunnan, China

Virology Journal, 2017
Background Rodents represent the most diverse mammals on the planet and are important reservoirs of human pathogens. Coronaviruses infect various animals, but to date, relatively few coronaviruses have been identified in rodents worldwide.
Xing-Yi Ge, Wei-Hong Yang, Ji-Hua Zhou, Bei Li, Wei Zhang, Zheng-Li Shi, Yun-Zhi Zhang   +6 more
doaj   +1 more source

Potent neutralising monoclonal antibodies targeting the spike of NL63 coronavirus

npj Viruses
NL63 is an alphacoronavirus that uses the same ACE2 receptor as SARS-CoV and SARS-CoV-2, but generally causes mild respiratory illness. In a cohort of healthy adults, we characterised humoral responses against NL63 spike and isolated a panel of human ...
Wen Shi Lee, George Taiaroa, Robyn Esterbauer, Meghan Conlan, Jessica A. Neil, Matthew J. Gartner, Monique Smith, Mingyang Wang, Rory A. Shepherd, Thomas Tran, Phillip Pymm, Lara S. U. Schwab, Andrew Kelly, Ellie Reilly, Thakshila Amarasena, Bruce D. Wines, P. Mark Hogarth, Jennifer A. Juno, Stephen J. Kent, Hyon-Xhi Tan, Kanta Subbarao, Adam K. Wheatley   +21 more
doaj   +1 more source

Unraveling Algerian bat coronaviruses: from initial detection to genome recovery and co-infection discovery

International Journal of Infectious Diseases
Introduction: Bats, known as main reservoirs for coronaviruses such as SARS-CoV and SARS-CoV-2, carry these viruses asymptomatically thanks to their unique immune systems.
Dr Safia Zeghbib, Zsófia Tauber, Dr Tamás Görföl, Karimane Malek Zeghbib, Dr Mourad Ahmim, Dr Gábor Kemenesi   +5 more
doaj   +1 more source

Crystal Structures of Fusion Cores from CCoV-HuPn-2018 and SADS-CoV

Viruses
Cross-species spillover to humans of coronaviruses (CoVs) from wildlife animal reservoirs poses marked and global threats to human and animal health. Recently, sporadic infection of canine coronavirus–human pneumonia-2018 (CCoV-HuPn-2018) in hospitalized
Fulian Wang, Guang Yang, Lei Yan
doaj   +1 more source

Presence of Alphacoronavirus in Tree- and Crevice-Dwelling Bats from Portugal

Viruses
Coronaviruses (CoVs) are RNA viruses capable of infecting a wide range of hosts, including mammals and birds, and have caused significant epidemics such as the ongoing COVID-19 pandemic.
Mahima Hemnani, Priscilla Gomes da Silva, Gertrude Thompson, Patrícia Poeta, Hugo Rebelo, João R. Mesquita   +5 more
doaj   +1 more source

Detection and complete genome characterisation of bat coronaviruses from Ghana. [PDF]

Arch Virol
El-Duah P, Yeboah R, Melchert J, Tasiame W, Nyarko-Afriyie E, Sylverken AA, Owusu M, Adu-Sarkodie Y, Drosten C, Corman VM.   +9 more
europepmc   +1 more source