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Host responses to alphavirus infection

Immunological Reviews, 2008
Summary: Members of the Alphavirus genus are classified into New World and Old World groups based upon their disease characteristics and primary areas of endemicity. The two groups exhibit noteworthy differences in pathogenesis during human infection, with Old World viruses primarily causing febrile and arthritogenic diseases and the New World viruses
Kate D, Ryman, William B, Klimstra
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Alphavirus infections in salmonids – a review

Journal of Fish Diseases, 2007
AbstractThe first alphavirus to be isolated from fish was recorded in 1995 with the isolation of salmon pancreas disease virus from Atlantic salmon, Salmo salar L., in Ireland. Subsequently, the closely related sleeping disease virus was isolated from rainbow trout, Oncorhynchus mykiss (Walbaum), in France.
M F, McLoughlin, D A, Graham
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An eruption associated with alphavirus infection

British Journal of Dermatology, 1996
Some alphaviruses, e.g. Sindbis, cause an acute febrile illness associated with papular rashes and arthralgia. The diagnosis is usually serological and, hence, the histopathology of the rashes has been poorly elucidated. We report on two patients with rapidly healing eruptions associated with Sindbis virus infection.
P, Autio, K M, Niemi, A L, Kariniemi
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The effects of alphavirus infection on neurons

Annals of Neurology, 1994
Sindbis virus is an alphavirus that causes encephalitis in mice. The primary target cells for central nervous system infection are neurons. The outcome of neuronal infection is dependent on the age of the mouse at the time of infection (maturity of the neuron) and the strain of virus used for infection (virulence of the virus).
D E, Griffin   +3 more
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Animal models of alphavirus infection and human disease

2022
Alphaviruses are a large group (>30 species) of enveloped, positive-strand RNA viruses. The re-emergence of mosquito-transmitted alphaviruses associated with human diseases ranging from severe and potentially fatal neurological disease to chronic arthritic disease highlights the need to understand the biology and pathogenesis of alphaviruses.
Cormac J, Lucas, Thomas E, Morrison
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Cross‐reactive Cytotoxic T Cells to Alphavirus Infection

Scandinavian Journal of Immunology, 1979
Secondary Tc cells immune to alphaviruses (BEB, SIN and SFV) cross‐react between serologically defined subgroups at the level of target lysis and at the level of induction of response. Despite this apparently complete Tc cell cross‐reactivity between BFB, SIN and SFV, amisera raised against BEB and SIN showed virus specificity in their ability to block
A, Mullbacher   +2 more
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