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Age-dependent susceptibility to fatal encephalitis: alphavirus infection of neurons
1994Sindbis virus encephalitis in mice provides a model for studying age-dependent susceptibility to acute viral encephalitis. The AR339 strain of SV causes fatal encephalitis in newborn mice, but weanling mice recover uneventfully. Increased virulence for older mice is associated with a single amino acid change from Gln to His at position 55 of the E2 ...
D E, Griffin +4 more
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A molecular understanding of alphavirus entry and antibody protection
Nature Reviews Microbiology, 2022Michael Diamond +2 more
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Therapeutic alphavirus cross-reactive E1 human antibodies inhibit viral egress
Cell, 2021Robert Carnahan +2 more
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Role of Antibodies in Controlling Alphavirus Infection of Neurons
2001D E, Griffin +4 more
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Processing of alphavirus-specific proteins in infected cells.
Medical biology, 1976The RNA of the alphaviruses contains the genetic information for both the non-structural and the structural polypeptides. The former are contained in the initial two-thirds of the sequence (from the 5'-terminus) and are read directly from the virus particle RNA, but whether post-translational cleavage is involved or not is not known.
openaire +1 more source
Agua Salud Alphavirus Infection, Dissemination and Transmission in Aedes aegypti Mosquitoes
Viruses, 2023Vattipally B Sreenu +2 more
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Age has a role in driving host immunopathological response to alphavirus infection
Immunology, 2017Yi-Hao Chan, Lisa Ng
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