Results 101 to 110 of about 10,706 (212)

Nanocoating with plant-derived pectins activates osteoblast response in vitro [PDF]

, 2016
: A new strategy to improve osseointegration of implants is to stimulate adhesion of bone cells, bone matrix formation, and mineralization at the implant surface by modifying surface coating on the nanoscale level.
Buttgereit, F., Detert, J., Folkert, J., Gaber, T., Gurzawska, K., Meresta, A., Miksch, K., Pischon, N.   +7 more
core   +2 more sources

Soluble Sema4D From γδ T Cells Exerts Osteoblast Inhibition via Plexin‐B/mTOR Signalling Contributing to Pathogenesis of Bisphosphonate‐Related Osteonecrosis of the Jaws

Cell Proliferation, EarlyView.
Schematic summarizing the pathway of sSema4D from γδ T cells inhibiting osteoblast differentiation in BRONJ. ABSTRACT Bisphosphonate‐related osteonecrosis of the jaw (BRONJ) is a severe complication in patients undergoing long‐term bisphosphonate therapy, while our knowledge on the pathogenesis of BRONJ is far from sufficient.
Lingling Ou, Shijia Qiao, Zhuoyi Liao, Xiner Tan, Hui Huang, Zhiyan Zhou, Ruhui Luo, Weijun Zeng, Yan Yang, Zhongxuan Zhang, Jingchen Chen, Shengli Wang, Yiqin Jiang, Jianlei Hao, Yuqin Shen, Longquan Shao   +15 more
wiley   +1 more source

LincRNA-ASAO promotes dental pulp repair through interacting with PTBP1 to increase ALPL alternative splicing

Stem Cell Research & Therapy
Background Alternative splicing not only expands the genetic encoding of genes but also determines cellular activities. This study aimed to elucidate the regulation mechanism and biological functions of lincRNA-ASAO in the process of odontogenesis ...
Fuchun Fang, Xiaolan Guo, Sitong Liu, Longrui Dang, Zehao Chen, Yumeng Yang, Lu Chen, Jiahao Lin, Wei Qiu, Zhao Chen, Buling Wu   +10 more
doaj   +1 more source

Hypophosphatasia and its role in bone pathology in adults

Лечащий Врач, 2021
Pathogenesis and symptoms of hypophosphatasia were reviewed, in particular in adults, as well as methods of diagnostics and treatment.
K. E. Zotkina, O. M. Lesnyak
doaj  

Effect of Jagged1 on the expression of genes in regulation of osteoblast differentiation and bone mineralization ontology in human dental pulp and periodontal ligament cells

Journal of Oral Biology and Craniofacial Research, 2020
Objective: To define the effect of Jagged1 on the gene expression in osteoblast differentiation, regulation of osteoblast differentiation and regulation of bone mineralization ontology.
Kanokporn Hansamuit, Thanaphum Osathanon, Jaijam Suwanwela   +2 more
doaj   +1 more source

Targeted Alkaline Phosphatase Therapy Enhances Alveolar Bone Healing in X‐Linked Hypophosphatemia in Mice

Journal of Periodontal Research, EarlyView.
Effects of exogenous tissue‐nonspecific alkaline phosphatase (TNAP) were analyzed in the Hyp mouse model of X‐linked hypophosphatemia (XLH). Maxillary first molars were extracted from wild‐type (WT) and Hyp mice at 6 weeks, and collagen gel ± TNAP was placed in sockets. In one group of Hyp mice, submucosal injections of TNAP or saline were delivered at
Aonjittra Phanrungsuwan, Bella Donnelly, José Luis Millán, Brian L. Foster   +3 more
wiley   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

Genetic Profiling of MC3T3-E1 Cells in Different Media: Implications for In Vitro Screening Development

Biomedicines
Background/Objectives: The translation of in vitro biomaterial evaluations into successful clinical applications often fails due to discrepancies with in vivo results.
Makoto Izumiya, Hidehiko Nobuoka, Hono Endo, Rintaro Ueno, Masaki Mimura, Naoto Saito, Hisao Haniu   +6 more
doaj   +1 more source

Titanium alloys (AoN) and their involvement in osseointegration

Dental Research Journal, 2012
Background: Osseointegration is essential for a long-term successful and inflammation-free dental implant. Such a result depends on osteoblastic cells growth and differentiation at the tissue-implant interface.
Matteo Danza, Ilaria Zollino, Valentina Candotto, Francesca Cura, Francesco Carinci   +4 more
doaj   +1 more source

Impact of hydrogel stiffness on differentiation of human adipose-derived stem cell microspheroids [PDF]

, 2019
Hydrogels represent an attractive material platform for realization of three-dimensional (3D) tissue-engineered constructs, as they have tunable mechanical properties, are compatible with different types of cells, and resemble elements found in natural ...
Baudis, Stefan, Dubruel, Peter, Markovic, Marica, Ovsianikov, Aleksandr, Van Hoorick, Jasper, Van Vlierberghe, Sandra, Zerobin, Elise, Zigon-Branc, Sara   +7 more
core   +2 more sources