Results 61 to 70 of about 2,420,347 (314)
The project MinE databrowser: bringing large-scale whole-genome sequencing in ALS to researchers and the public [PDF]
, 2019 Amyotrophic lateral sclerosis (ALS) is a rapidly progressive fatal neurodegenerative disease affecting one in 350 people. The aim of Project MinE is to elucidate the pathophysiology of ALS through whole-genome sequencing at least 15,000 ALS patients and ...
Project MinE ALS Sequencing Consortium¶
core
Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability [PDF]
, 2015 This work has been supported by: Motor Neurone Disease Association (G.B.M., S.C. and C.E.S.); Euan MacDonald Centre (G.B.M. and S.C.); European Research Council (L.V.); Cambridge Hospitals National Institute for Health Research Biomedical Research Center
Foster, Joshua D. +15 more
core +1 more source
Rare Variant Burden Analysis within Enhancers Identifies CAV1 as an ALS Risk Gene [PDF]
, 2020 Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease. CAV1 and CAV2 organize membrane lipid rafts (MLRs) important for cell signaling and neuronal survival, and overexpression of CAV1 ameliorates ALS phenotypes in vivo.
Allen, Samantha +27 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine +21 more
wiley +1 more source
ALS Focus Wave 4 – Telehealth Survey
The NeuroVERSE record contains the following files: ALSFocusWave4_DataDictionary.xlsx – This is the data dictionary for surveys fielded in ALS Focus Wave 4.
The ALS Association
core +1 more source
ATXN2 and its neighbouring gene SH2B3 are associated with increased ALS risk in the Turkish population [PDF]
, 2012 Expansions of the polyglutamine (polyQ) domain (≥34) in Ataxin-2 (ATXN2) are the primary cause of spinocerebellar ataxia type 2 (SCA2). Recent studies reported that intermediate-length (27–33) expansions increase the risk of Amyotrophic Lateral Sclerosis
Hilmi Özçelik (5648923) +35 more
core +2 more sources
Біоінформатичний аналіз потенційних ALS/AHAS-білків моркви (Daucus carota)
Фактори експериментальної еволюції організмів, 2016 Aim. One of the main challenges in plant breeding is creating of herbicide resistant cultivars and hybrids. Carrot is a very useful model plant for optimization of new plant breeding methods to create ALS-inhibitor-resistant plants due to its ...
А. В. Сидоров +5 more
doaj
First Report of Multiple Resistance in Galium aparine to ALS-Inhibiting and Auxin Analog Herbicides in Kermanshah, Iran [PDF]
Planta Daninha, 2019 : Catchweed Bedstraw (Galium aparine) is a problematic weed, which has become increasingly difficult to control with herbicides in Iran. The aim of this study was to screen selected putative-resistant populations of G.
I. NOSRATTI, A. MUHAMMADYARI
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi +9 more
wiley +1 more source
Weed TechnologyBlackgrass is a highly competitive weed in wheat fields and has increasingly evolved resistance to acetolactate synthase (ALS)-inhibiting herbicides. Ten field populations were screened, resulting in the selection of one highly resistant population (R-06)
Mujeeba Fida +7 more
doaj +1 more source