Results 51 to 60 of about 2,287,133 (314)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Characterisation and molecular basis of ALS inhibitor resistance in the grass weed Alopecurus myosuroides

, 2008
Several UK populations of the grass weed Alopecurus myosuroides were identified where high proportions of individuals showed resistance to the acetolactate synthase (ALS)-inhibiting herbicides, mesosulfuron-methyl + iodosulfuron-methyl sodium mixture and
Moss, S. R., Marshall, R.
core   +1 more source

Dissipation of nitrapyrin (nitrification inhibitor) in subtropical soils [PDF]

, 2019
Nitrapyrin (2-chloro-6-(trichloromethyl)pyridine) is a specific nitrification inhibitor, applied in soils for reducing the nitrification process of nitrogenous fertilizers.
Srivastava, Anjana
core   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability [PDF]

, 2015
This work has been supported by: Motor Neurone Disease Association (G.B.M., S.C. and C.E.S.); Euan MacDonald Centre (G.B.M. and S.C.); European Research Council (L.V.); Cambridge Hospitals National Institute for Health Research Biomedical Research Center
Foster, Joshua D., Shaw, Christopher E., Cleary, Elaine M., Cleary, Elaine M, Foster, Joshua D, Miles, Gareth B, Devlin, Anna-Claire, Geti, Imbisaat, Cleary, Elaine Marie, Miles, Gareth B., Borooah, Shyamanga, Devlin, Anna Claire, Shaw, Christopher E, Vallier, Ludovic, Burr, Karen, Chandran, Siddharthan   +15 more
core   +1 more source

Rare Variant Burden Analysis within Enhancers Identifies CAV1 as an ALS Risk Gene [PDF]

, 2020
Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease. CAV1 and CAV2 organize membrane lipid rafts (MLRs) important for cell signaling and neuronal survival, and overexpression of CAV1 ameliorates ALS phenotypes in vivo.
Allen, Samantha, Shaw, Pamela J., Veldink, Jan H., Eitan, Chen, Moll, Tobias, Nezhad, Helia Ghahremani, Snyder, Michael P., Cooper-Knock, Johnathan, Al-Chalabi, Ammar, Kirby, Janine, Fishilevich, Simon, Morrison, Karen E., Yacovzada, Nancy Y., Elhaik, Eran, Shaw, Christopher E., Zhang, Sai, Farhan, Sali, Hornstein, Eran, Cauchi, Ruben J., Ghahremani Nezhad, Helia, Ehilak, Eran, Bose, Daniel, Lancet, Doron, Franklin, John P., Iacoangeli, Alfredo, Project MinE ALS Sequencing Consortium, Kenna, Kevin P., Celadova, Petra   +27 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

ALS Focus Wave 3 – Caregiver Needs Survey

The NeuroVERSE record contains the following files: ALSFocusWave3_DataDictionary.xlsx – This is the data dictionary for surveys fielded in ALS Focus Wave 3.
The ALS Association
core   +1 more source

The project MinE databrowser: bringing large-scale whole-genome sequencing in ALS to researchers and the public [PDF]

, 2019
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive fatal neurodegenerative disease affecting one in 350 people. The aim of Project MinE is to elucidate the pathophysiology of ALS through whole-genome sequencing at least 15,000 ALS patients and ...
Project MinE ALS Sequencing Consortium¶
core