Results 31 to 40 of about 2,287,133 (314)
PLoS ONE, 2012 BackgroundAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive death of motor neurons. Although the pathogenesis of ALS remains unclear, several cellular processes are known to be involved, including ...
Ryu Katsumata +9 more
doaj +1 more source
ING4 (inhibitor of growth family, member 4) [PDF]
, 2011 Review on ING4 (inhibitor of growth family, member 4), with data on DNA, on the protein encoded, and where the gene is ...
Miranda, C, Greco, A
core +1 more source
Multiple mutations in the EPSPS and ALS genes of Amaranthus hybridus underlie resistance to glyphosate and ALS inhibitors [PDF]
Scientific Reports, 2020 AbstractAmaranthus hybridus is one of the main weed species in Córdoba, Argentina. Until recently, this weed was effectively controlled with recurrent use of glyphosate. However, a population exhibiting multiple resistance (MR2) to glyphosate and imazamox appeared in a glyphosate resistant (GR) soybean field, with levels of resistance up to 93 and 38 ...
Maria J. García +6 more
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Investigation of ammonium–lauric salt as shale swelling inhibitor and a mechanism study
Adsorption Science & Technology, 2019 In this work, a series of ammonium–lauric salts (ALS) was prepared with lauric acid and amines as small molecular shale swelling inhibitor. The inhibitors were screened by the linear expansion test first, and the result shows that the inhibitor prepared ...
Jie Zhang +5 more
doaj +1 more source
Compassionate Use of the ROCK Inhibitor Fasudil in Three Patients With Amyotrophic Lateral Sclerosis
Frontiers in Neurology, 2020 The Rho kinase (ROCK) inhibitor Fasudil is a promising drug for a disease-modifying therapy of amyotrophic lateral sclerosis (ALS). In preclinical models, Fasudil was shown to increase motor neuron survival, inhibit axonal degeneration, enhance axonal ...
Jan C. Koch +7 more
doaj +1 more source
Occurrence and Mechanism of Papaver rhoeas ALS Inhibitors Resistance in Poland
Agriculture, 2022 Herbicide resistance in weeds, including corn poppy (Papaver rhoeas L.), is an increasing problem compromising global crop production. The aims of this study were to evaluate the susceptibility of P. rhoeas populations in Poland to acetolactate synthase (ALS) inhibitors and elucidate their mechanisms of resistance.
Marta Stankiewicz-Kosyl +13 more
openaire +3 more sources
Edaravone: A new hope for patients with amyotrophic lateral sclerosis
Apollo Medicine, 2019 Although the exact pathophysiology of amyotrophic lateral sclerosis (ALS) remains unclear, oxidative stress is known to play a pivotal role. There is no cure for ALS, but there are two drugs available to slow the progression of the disease. Till recently,
Shivangi Garg +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Proteasome Inhibitors to Treat AL Amyloidosis
, 2016 Amyloidoses represent a highly heterogeneous group of diseases characterized by the abnormal production and accumulation of abnormal, insoluble amyloid proteins in various tissues leading to organ dysfunction. Light‐chain (AL) amyloidosis is the most common form of systemic amyloidosis and is characterized by extracellular deposi‐ tion of pathologic ...
James J. Driscoll, Saulius Girnius
openaire +2 more sources
Weed TechnologyHerbicide-resistant weeds are fast becoming a substantial global problem, causing significant crop losses and food insecurity. Late detection of resistant weeds leads to increasing economic losses.
Pauline Victoria Estrada +3 more
doaj +1 more source