Results 111 to 120 of about 2,396,315 (311)

Cysteine proteinase inhibitors: purification and gene isolation [PDF]

open access: yes, 1989
Genetic engineering has produced a transgenic insect- resistant plant which produces a serine protease inhibitor (Hilder et al., 1987). More insects can be targetted if a plant can be made to produce thiol protease inhibitors.
Fones, Angela Mei Ling
core  

The cost and availability of rare earth-based corrosion inhibitors

open access: yes, 2014
Rare earths have been studied extensively as corrosion inhibitors for a range of metals. However, there is little information about the viability of the rare earths as inhibitors from the perspective of price and availability.
Mol, J.M.C.   +8 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Dispersal and genetic variability of Sonchus oleraceus L. in relation to its resistance to ALS-inhibiting herbicides. [PDF]

open access: yes, 2011
The work described in this thesis investigates the existence and level of acetolactate synthase (ALS)-inhibiting herbicide resistance in Sonchus oleraceus in Australia. It further discusses the sensitivity of different S.
St. John-Sweeting, Robin S.
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Studies on a-amylase inhibitors from seeds of sorghum bicolor [PDF]

open access: yes, 1991
Six inhibitors (Slal, SIa2, SIa3, SIa4, SIa5 and SIa6) of a-amylase from mammalian, insect, bacterial and fungal sources were purified from seeds of Sorghum bicolor (L) Moench by saline extraction, precipitation with ammonium sulphate, affinity ...
Junior, Carlos Bloch
core  

Differential effects of low molecular weight inhibitors on the conformation and the immunologic function of the adhesion receptor LFA-1 [PDF]

open access: yes, 2004
Previous studies of our group 1,2 and by others 3 on the isolated ligand binding domain of LFA-1 (αL I domain) have suggested that some LFA-1 inhibitors act allosterically while other inhibitors were proposed to competitively block the LFA- 1/ligand ...
Welzenbach, Karl Albert
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Inhibitors of PCSK9 enzyme as a drug for hypercholesterolemia

open access: yes, 2020
New class of drugs, fully humanized monoclonal antibodies, evolocumab and alirocumab, work as PCSK9 inhibitors. Evolocumab and alirocumab bind free plasma PCSK9 and lead to its degradation, as a result, less free PCSK9 is available in the plasma to bind ...
Nashashibi, Mary
core  

Non-target-site resistance to ALS inhibitors in waterhemp [PDF]

open access: yes, 2014
The acetolactate synthase (ALS) enzyme, or acetohydroxyacid synthase (AHAS) enzyme, is an essential enzyme in branched-chain amino acid biosynthesis, and is the target site of five families of herbicides referred to as ALS inhibitors.
Guo, Jiaqi
core  

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