Results 51 to 60 of about 1,939,981 (312)

A randomized double-blind clinical trial on safety and efficacy of tauroursodeoxycholic acid (TUDCA) as add-on treatment in patients affected by amyotrophic lateral sclerosis (ALS): the statistical analysis plan of TUDCA-ALS trial [PDF]

, 2023
Background: Amyotrophic lateral sclerosis (ALS) is a highly debilitating neurodegenerative condition. Despite recent advancements in understanding the molecular mechanisms underlying ALS, there have been no significant improvements in therapeutic options
Puopolo, Maria, Lo Giudice, Maria, Van Damme, Philip, Alegiani, Stefania Spila, Corcia, Philippe, Mayer, Flavia, Ludolph, Albert Christian, McDermott, Christopher J., TUDCA-ALS Study Group, Albanese, Alberto, Cipriani, Marta, Dickie, Brian, Van den Berg, Leonard H., Nicolini, Gabriele, Lombardo, Flavia L., Vanacore, Nicola, Hardiman, Orla   +16 more
core  

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source

Identification of acetolactate synthase resistant Amaranthus retroflexus in Ukraine

Regulatory Mechanisms in Biosystems, 2022
The problem of weed resistance to herbicides has become very important in the last decade and threatens to dramatically reduce the productivity and profitability of modern crop production. Herbicides – ALS inhibitors dominate among current herbicides and
L. M. Mykhalska, V. V. Schwartau
doaj   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Lern(er)-Grammatik für Deutsch als Fremdsprache [PDF]

, 1993
Schmidt R. Lern(er)-Grammatik für Deutsch als Fremdsprache. In: Wolff A, Jahrestagung Deutsch als Fremdsprache <18, 1990, Bonn>, Fachverband Deutsch als Fremdsprache, eds. Deutsch als Fremdsprache im europäischen Binnenmarkt.
Schmidt, Reiner, Jahrestagung Deutsch als Fremdsprache <18, 1990, Bonn>, Fachverband Deutsch als Fremdsprache, Wolff, Armin   +3 more
core  

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan, Mariah Wright‐Nadkarni, Mohamed S. Abdelbaki, Girish Dhall   +3 more
wiley   +1 more source

Whole-genome sequencing reveals that variants in the Interleukin 18 Receptor Accessory Protein 3'UTR protect against ALS

, 2022
The noncoding genome is substantially larger than the protein-coding genome but has been largely unexplored by genetic association studies. Here, we performed region-based rare variant association analysis of >25,000 variants in untranslated regions of 6,
Project MinE ALS Sequencing Consortium
core  

Histone deacetylase 4 protects from denervation and skeletal muscle atrophy in a murine model of amyotrophic lateral sclerosisResearch in context

EBioMedicine, 2019
Background: Histone deacetylase 4 (HDAC4) has been proposed as a target for Amyotrophic Lateral Sclerosis (ALS) because it mediates nerve-skeletal muscle interaction and since its expression in skeletal muscle correlates with the severity of the disease.
Eva Pigna, Elena Simonazzi, Krizia Sanna, Krzysztof Marian Bernadzki, Tomek Proszynski, Constantin Heil, Daniela Palacios, Sergio Adamo, Viviana Moresi   +8 more
doaj   +1 more source

The application of 1.8-naphthalic anhydride to control ALS-herbicide resistant barnyardgrass with graminicides

Карантин і захист рослин, 2020
Goal. Investigate the possibility to use 1,8-naphthalic anhydride metabolism inductor to control acetolactate synthase (ALS) inhibitor-resistant biotype of common graminicides of aryloxyphenoxypropionic acid class in rice. Methodology. The interaction
V. Schwartau, L. Mykhalska
doaj   +1 more source

Sequential application of herbicide options for controlling Conyza sumatrensis in soybean pre-sowing

Revista de la Facultad de Ciencias Agrarias, 2022
The aim of this study was to evaluate the efficacy of sequentially applied herbicides to control Conyza sumatrensis, one of the most widely distributed weeds worldwide, in soybean pre-sowing burndown. The study was conducted under field conditions in
Leandro Paiola Albrecht, Alfredo Junior Paiola Albrecht, André Felipe Moreira Silva, Romulo Augusto Ramos, Karine Yone Rodrigues da Costa, Gabriel Viana de Araújo, Tamara Thaís Mundt, Corina Colombari   +7 more
doaj   +1 more source