Results 11 to 20 of about 112,765 (306)

Occurrence and Mechanism of Papaver rhoeas ALS Inhibitors Resistance in Poland

Agriculture, 2022
Herbicide resistance in weeds, including corn poppy (Papaver rhoeas L.), is an increasing problem compromising global crop production. The aims of this study were to evaluate the susceptibility of P. rhoeas populations in Poland to acetolactate synthase (
Marta Stankiewicz-Kosyl, Małgorzata Haliniarz, Mariola Wrochna, Aleksandra Obrępalska-Stęplowska, Piotr Kuc, Justyna Łukasz, Marzena Wińska-Krysiak, Barbara Wrzesińska-Krupa, Joanna Puła, Cezary Podsiadło, Krzysztof Domaradzki, Mariusz Piekarczyk, Marcin Bednarczyk, Katarzyna Marcinkowska   +13 more
doaj   +2 more sources

Model for metabolic resistance against ALS inhibitors

Julius-Kühn-Archiv, 2014
Due to herbicide selection pressure metabolic resistance has evolved in many weed species. In this paper we analyse the interaction between the branched chain amino acid (BBC) pathway and detoxifying pathways for herbicide breakdown.
Richter, Otto, Langemann, Dirk, Beffa, Roland   +2 more
doaj   +2 more sources

Multiple mutations in the EPSPS and ALS genes of Amaranthus hybridus underlie resistance to glyphosate and ALS inhibitors. [PDF]

Sci Rep, 2020
AbstractAmaranthus hybridus is one of the main weed species in Córdoba, Argentina. Until recently, this weed was effectively controlled with recurrent use of glyphosate. However, a population exhibiting multiple resistance (MR2) to glyphosate and imazamox appeared in a glyphosate resistant (GR) soybean field, with levels of resistance up to 93 and 38 ...
García MJ, Palma-Bautista C, Vazquez-Garcia JG, Rojano-Delgado AM, Osuna MD, Torra J, De Prado R.   +6 more
europepmc   +6 more sources

Bromodomain inhibitors regulate the C9ORF72 locus in ALS [PDF]

Experimental Neurology, 2015
A hexanucleotide repeat expansion residing within the C9ORF72 gene represents the most common known cause of amyotrophic lateral sclerosis (ALS) and places the disease among a growing family of repeat expansion disorders. The presence of RNA foci, repeat-associated translation products, and sequestration of RNA binding proteins suggests that toxic RNA ...
Zane, Zeier, Rustam, Esanov, Kinsley C, Belle, Claude-Henry, Volmar, Andrea L, Johnstone, Paul, Halley, Brooke A, DeRosa, Nathalie, Khoury, Marka, van Blitterswijk, Rosa, Rademakers, Jeffrey, Albert, Shaun P, Brothers, Joanne, Wuu, Derek M, Dykxhoorn, Michael, Benatar, Claes, Wahlestedt   +15 more
openaire   +2 more sources

Janus kinase inhibitors are potential therapeutics for amyotrophic lateral sclerosis

Translational Neurodegeneration, 2023
Amyotrophic lateral sclerosis (ALS) is a poorly treated multifactorial neurodegenerative disease associated with multiple cell types and subcellular organelles.
Peter J. Richardson, Daniel P. Smith, Alex de Giorgio, Xenia Snetkov, Joshua Almond-Thynne, Sara Cronin, Richard J. Mead, Christopher J. McDermott, Pamela J. Shaw   +8 more
doaj   +1 more source

The effect of low growth temperature on Hill reaction and Photosystem 1 activities in three biotypes of Kochia scoparia (L.) Schrad. with different sensitivity to atrazine and ALS-inhibiting herbicides

Plant, Soil and Environment, 2004
A possible influence of low growth temperature on the photochemical activity of isolated mesophyll chloroplasts was studied in three biotypes of kochia [Kochia scoparia (L.) Schrad.] that showed either double resistance to both atrazine and acetolactate ...
D. Holá, M. Kočová, O. Rothová, D. Chodová, J. Mikulka   +4 more
doaj   +1 more source

Synergistic association of resveratrol and histone deacetylase inhibitors as treatment in amyotrophic lateral sclerosis

Frontiers in Pharmacology, 2022
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease associated with motor neuron degeneration, progressive paralysis and finally death. Despite the research efforts, currently there is no cure for ALS.
Edoardo Parrella, Vanessa Porrini, Ilaria Scambi, Michele M. Gennari, Cristina Gussago, Oluwamolakun Bankole, Marina Benarese, Raffaella Mariotti, Marina Pizzi   +8 more
doaj   +1 more source

Resistance to post-emergent herbicides is becoming common for grass weeds on New Zealand wheat and barley farms.

PLoS ONE, 2021
To estimate the prevalence of herbicide-resistant weeds, 87 wheat and barley farms were randomly surveyed in the Canterbury region of New Zealand. Over 600 weed seed samples from up to 10 mother plants per taxon depending on abundance, were collected ...
Christopher E Buddenhagen, Trevor K James, Zachary Ngow, Deborah L Hackell, M Phil Rolston, Richard J Chynoweth, Matilda Gunnarsson, Fengshuo Li, Kerry C Harrington, Hossein Ghanizadeh   +9 more
doaj   +1 more source

Lessons from LIMK1 enzymology and their impact on inhibitor design [PDF]

, 2019
LIM domain kinase 1 (LIMK1) is a key regulator of actin dynamics. It is thereby a potential therapeutic target for the prevention of fragile X syndrome and amyotrophic lateral sclerosis.
Beltrami, A, Bullock, Alexander, Canning, P, Chaikuad, A, Chatterjee, D, Knapp, S, Knaus, P, Mathea, S, Preuss, F, Salah, E, Tumber, A   +10 more
core   +2 more sources

Evolution der Herbizidresistenz in Alopecurus myosuroides und Apera spica-venti im deutschen Getreideanbau der letzten 15 Jahre

Julius-Kühn-Archiv, 2020
Das Vorkommen von Herbizidresistenzen bei Ungräsern nimmt in den letzten 30 Jahren in Deutschland kontinuierlich zu. Dies gilt sowohl für die Anzahl der betroffenen Arten, die regionale Verbreitung, den Resistenzgrad, die Anzahl der Aktivsubstanzen, der ...
Petersen, Jan, Raffel, Hans
doaj   +1 more source