Results 71 to 80 of about 1,939,981 (312)

Occurrence and Mechanisms Conferring Multiple Resistance to ALS-Inhibiting and Auxins Mimics Herbicides in Papaver rhoeas from Tunisia

open access: yesAgronomy
Herbicide-resistant corn poppy (Papaver rhoeas L.) is one of the most important broadleaved weeds and the number of resistant cases is still growing. The aims of this study were to confirm the resistance of P.
Myriem Chtourou   +5 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Inhibition of extracellular regulated kinase (ERK)-1/2 signaling pathway in the prevention of ALS: Target inhibitors and influences on neurological dysfunctions

open access: yesEuropean Journal of Cell Biology, 2021
Cell signal transduction pathways are essential modulators of several physiological and pathological processes in the brain. During overactivation, these signaling processes may lead to disease progression.
Rakesh Sahu   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

ALS Focus Wave 3 – Caregiver Needs Survey

open access: yes
The NeuroVERSE record contains the following files: ALSFocusWave3_DataDictionary.xlsx – This is the data dictionary for surveys fielded in ALS Focus Wave 3.
The ALS Association
core   +1 more source

The project MinE databrowser: bringing large-scale whole-genome sequencing in ALS to researchers and the public [PDF]

open access: yes, 2019
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive fatal neurodegenerative disease affecting one in 350 people. The aim of Project MinE is to elucidate the pathophysiology of ALS through whole-genome sequencing at least 15,000 ALS patients and ...
Project MinE ALS Sequencing Consortium¶
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

ALS Focus Wave 4 – Telehealth Survey

open access: yes
The NeuroVERSE record contains the following files: ALSFocusWave4_DataDictionary.xlsx – This is the data dictionary for surveys fielded in ALS Focus Wave 4.
The ALS Association
core   +1 more source

Development of resistance of Apera spica-venti (L.) P. Beauv. (Loose silky-bent) in Lower Saxony in 2013 - also increasingly against Pinoxaden

open access: yesJulius-Kühn-Archiv, 2014
Herbicide resistance has increased dramatically all over the world. Especially North America, South America and Australia are affected. In the last few years also in Europe different active ingredient groups become more and more ineffectively.
Wolber, Dirk Michael
doaj   +1 more source

Home - About - Disclaimer - Privacy