Results 21 to 30 of about 10,421 (208)

ALSPAC parents’ descriptions of childhood stresses in their parents and grandparents [PDF]

Wellcome Open Research, 2021
Background: There is evidence that childhood stresses or traumas influence individuals’ descendants’ health and wellbeing through epigenetic mechanisms. However, few longitudinal studies have details of such ancestral data.
Karen Birmingham, Yasmin Iles-Caven, Jean Golding   +2 more
openaire   +4 more sources

Cognitive functioning in anxiety and depression: Results from the ALSPAC cohort [PDF]

Royal Society Open Science, 2021
Abstract Background Understanding the nature of cognitive deficits in anxiety and depression may identify intervention targets and help prevent functional decline. This study used observational and genetic methods to investigate the association of anxiety and depression with emotion recognition ...
Steph Suddell, Liam Mahedy, Caroline Skirrow, Ian S. Penton-Voak, Marcus R. Munafò, Robyn E. Wootton   +5 more
openaire   +4 more sources

Association between the timing of childhood adversity and epigenetic patterns across childhood and adolescence: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC) prospective cohort [PDF]

, 2023
Background: Childhood adversity is a potent determinant of health across development and is associated with altered DNA methylation signatures, which might be more common in children exposed during sensitive periods in development.
Simpkin, Andrew J, Dunn, Erin C, Huang, Rae Chi, Lussier, Alexandre A, Schneper, Lisa, Fisher, Jonah, Wood, Natasha M, Melton, Phillip, Walton, Esther, Suderman, Matthew J, Cohen-Woods, Sarah, Notterman, Daniel A, Mitchell, Colter, Ressler, Kerry J, Zhu, Yiwen, Relton, Caroline L, Smith, Brooke J, Smith, Andrew D A C, Cerutti, Janine   +18 more
core   +1 more source

ALSPAC Mercury Study and Fish Consumers [PDF]

Environmental Health Perspectives, 2014
Golding et al. (2013) described regression analysis of dietary contributions to maternal blood mercury levels, nested within the Avon Longitudinal Study of Parents and Children (ALSPAC). Fish intake explained only about 7% of the variance in blood mercury, leading them to conclude somewhat cautiously that “limiting seafood intake during pregnancy may ...
Gochfeld, Michael, Burger, Joanna, Stern, Alan H., Ginsberg, Gary, Anderson, Henry   +4 more
openaire   +2 more sources

The Avon Longitudinal Study of Parents and Children - A resource for COVID-19 research: Generation 2 questionnaire data capture May-July 2020 [version 1; peer review: 2 approved, 1 approved with reservations]

Wellcome Open Research, 2020
The Avon Longitudinal Study of Parents and Children (ALSPAC) is a prospective population-based cohort study which recruited pregnant women in 1990-1992 from the Bristol area (UK).
Daniel Smith, Kate Northstone, Claire Bowring, Nicholas Wells, Michael Crawford, Rebecca M. Pearson, Amy Thomas, Ellen Brooks-Pollock, Deborah A. Lawlor, Nicholas John Timpson   +9 more
doaj   +1 more source

Prevalence and characteristics of autistic spectrum disorders in the ALSPAC cohort [PDF]

Developmental Medicine & Child Neurology, 2008
The aim of this study was to determine the prevalence of autistic spectrum disorder (ASD) within a large representative population sample: the Avon Longitudinal Study of Parents and Children (ALSPAC). Cases of ASD were identified from the clinical notes of children in the ALSPAC with a suspected developmental disorder and from the Pupil Level Annual ...
Williams, E, Thomas, K, Sidebotham, H, Emond, A   +3 more
openaire   +3 more sources

Defining ‘sensitive’ health status: a systematic approach using health code terminologies.

International Journal of Population Data Science, 2017
Objectives “Clearly, details about an individual’s mental health, for example, are generally much more ‘sensitive’ than whether they have a broken leg.” UK Information Commissioners Office There is a perceived wisdom – based on issues such as ...
Andy Boyd, Rosie Cornish, Jennifer Provis, Alison Teyhan, John Macleod   +4 more
doaj   +1 more source

Locus of control is associated with tobacco and alcohol consumption in young adults of the Avon Longitudinal Study of Parents and Children [PDF]

Royal Society Open Science, 2019
Individuals appraise events as a consequence of their own actions (i.e. internal locus of control, LoC) or as the outcome of chance or others' will (i.e. external LoC).
G. Lassi, A. E. Taylor, L. Mahedy, J. Heron, T. Eisen, M. R. Munafò   +5 more
doaj   +1 more source

Pathways between childhood victimization and psychosis-like symptoms in the ALSPAC Birth Cohort [PDF]

, 2013
Background: Several large population-based studies have demonstrated associations between adverse childhood experiences and later development of psychotic symptoms.
Lewis, G., Maughan, B., Fisher, H. L., Lewis, Glyn, Fisher, Helen L; id_orcid, Schreier, Andrea, Lewis, Glyn H, Maughan, Barbara, Maughan, Barbara; id_orcid, Munafo, Marcus R., Wolke, D., Wolke, Dieter, Fisher, H., Zammit, Stanley, Munafò, Marcus R, Munafo, M. R., Schreier, A.   +16 more
core   +1 more source

Epigenomics of being bullied: changes in DNA methylation following bullying exposure

Epigenetics, 2020
Bullying among children is ubiquitous and associated with pervasive mental health problems. However, little is known about the biological pathways that change after exposure to bullying.
Rosa H. Mulder, Esther Walton, Alexander Neumann, Lotte C. Houtepen, Janine F. Felix, Marian J. Bakermans-Kranenburg, Matthew Suderman, Henning Tiemeier, Marinus H. van IJzendoorn, Caroline L. Relton, Charlotte A. M. Cecil   +10 more
doaj   +1 more source