Results 41 to 50 of about 19,041 (222)

Dysglycaemia, Inflammation and Psychosis: Findings From the UK ALSPAC Birth Cohort [PDF]

Schizophrenia Bulletin, 2018
BACKGROUND: Psychosis is associated with both dysglycaemia and low-grade inflammation, but population-based studies investigating the interplay between these factors are scarce. AIMS: (1) To explore the direction of association between markers of dysglycaemia, inflammation and psychotic experiences (PEs); and (2) To explore whether dysglycaemia ...
Perry, Benjamin Ian, Upthegrove, Rachel, Thompson, Andrew, Marwaha, Steven, Zammit, Stanley, Singh, Swaran Preet, Khandaker, Golam   +6 more
openaire   +6 more sources

Longitudinal population subgroups of CRP and risk of depression in the ALSPAC birth cohort [PDF]

Comprehensive Psychiatry, 2020
BACKGROUND: Meta-analyses confirm increased circulating C-reactive protein (CRP) levels in depression. Longitudinal studies have linked one-off measurements of CRP at baseline with increased risk of developing depressive symptoms subsequently at follow-up, but studies with repeat CRP measures from the same individuals are scarce.
Emanuele F. Osimo, Jan Stochl, Stan Zammit, Glyn Lewis, Peter B. Jones, Golam M. Khandaker   +5 more
openaire   +8 more sources

Childhood diet and behavioural problems: results from the ALSPAC cohort [PDF]

European Journal of Clinical Nutrition, 2011
To investigate whether a 'junk food' diet at 81 months of age is associated with the development of behavioural problems over the following 16 months.The study used data from the Avon Longitudinal Study of Parents and Children (ALSPAC) and 12,942 children were included. The main outcome measure was behavioural problems, measured using the Strengths and
Peacock, P, Lewis, G, Northstone, K, Wiles, NJ   +3 more
openaire   +2 more sources

Prenatal anxiety, breastfeeding and child growth and puberty: linking evolutionary models with human cohort studies

Annals of Human Biology, 2020
Background: Stress experienced by mothers during pregnancy can have both immediate and long-term effects on child development, potentially mediated by breastfeeding.
Sinead English, India Wright, Verity Ashburn, Gemma Ford, Doretta Caramaschi   +4 more
doaj   +1 more source

Genome-wide association study identifies common and low-frequency variants at the AMHgene locus that strongly predict serum AMH levels in males [PDF]

, 2016
Anti-Müllerian hormone (AMH) is an essential messenger of sexual differentiation in the foetus and is an emerging biomarker of postnatal reproductive function in females.
Day, Felix R., Lawlor, Debbie A., McMahon, George, Nelson, Scott M., Perry, John R.B., Ring, Susan M.   +5 more
core   +1 more source

Data resource profile: Alspac datacatalog schema and Alspac omics datacatalog

, 2023
The Avon Longitudinal Study of Parents and Children (ALSPAC) (1) (2) is a long-term cohort study that has been collecting data on the health and development of children and their families since 1991. In recent years, ALSPAC has collected a large amount of omics data, including genetic ar- ray, methylation, and gene expression data.
openaire   +1 more source

The second generation of The Avon Longitudinal Study of Parents and Children (ALSPAC-G2): a cohort profile [version 2; peer review: 2 approved]

Wellcome Open Research, 2019
Background: The Avon Longitudinal Study of Parents and Children-Generation 2 (ALSPAC-G2) was set up to provide a unique multi-generational cohort. It builds on the existing ALSPAC resource, which recruited 14,541 pregnancies to women resident in the ...
Deborah A. Lawlor, Melanie Lewcock, Louise Rena-Jones, Claire Rollings, Vikki Yip, Daniel Smith, Rebecca M. Pearson, Laura Johnson, Louise A. C. Millard, Nashita Patel, Andy Skinner, Kate Tilling, ALSPAC Executive   +12 more
doaj   +1 more source

Sex-specific longitudinal association of DNA methylation with lung function

ERJ Open Research, 2021
Investigating whether DNA methylation (DNA-M) at an earlier age is associated with lung function at a later age and whether this relationship differs by sex could enable prediction of future lung function deficit.
Shadia Khan Sunny, Hongmei Zhang, Caroline L. Relton, Susan Ring, Latha Kadalayil, Fawaz Mzayek, Susan Ewart, John W. Holloway, S. Hasan Arshad   +8 more
doaj   +1 more source

Cis and Trans Effects of Human Genomic Variants on Gene Expression [PDF]

, 2014
This work was funded by the Louis-Jeantet Foundation (http://www.jeantet.ch/), the European Research Council (Grant ID: 260927 http://erc.europa.eu/), the Swiss National Foundation (Grant ID: 130342 http://www.snf.ch), NCCR Frontiers In Genetics (http ...
A Boyd, AC Nica, AC Nica, AH Talukder, Alfonso Buil, AR Wood, AS Dimas, BE Stranger, BE Stranger, BU Schraml, C Wallace, Christopher David Brown, David M. Evans, DF Conrad, DJ Gaffney, DL Nicolae, DM Greenawalt, Donald F. Conrad, E Grundberg, E Klopocki, EE Schadt, Emmanouil T. Dermitzakis, George Davey Smith, GR Abecasis, H Huang, HJ Westra, J Ding, J Millstein, J Zhu, JD Storey, JE Powell, JK Pickrell, John P. Kemp, Julien Bryois, K Hildner, Karen M. Ho, LA Hindorff, M Gutierrez-Arcelus, M Scutari, Matthew Hurles, ND Miller, NL Barbosa-Morais, Panos Deloukas, RW Jones, SB Montgomery, SB Montgomery, SJ Loughran, Stephen B. Montgomery, Susan Ring, T Lappalainen, TR Insel, W Wang, Y Li, Y Li   +53 more
core   +5 more sources

Age at puberty and accelerometer-measured physical activity: Findings from two independent UK cohorts

Annals of Human Biology, 2020
Background It is unclear if puberty timing influences future physical activity (PA). Aim To investigate the association of puberty timing with PA across adolescence and adulthood. Subjects and methods Data were from two British cohorts. Participants from
Ahmed Ehakeem, Celia L. Gregson, Jon H. Tobias, Deborah A. Lawlor   +3 more
doaj   +1 more source