Phytotherapeutic Analysis of Chloroform-Based Fractions of Alstonia scholaris and Wrightia tinctoria Extracts Reveals Potent Anti-Psoriatic Activity: An In Vitro and In Vivo Study [PDF]
PharmaceuticalsBackground/Objectives: Psoriasis, a prevalent dermatological disorder, poses therapeutic challenges due to limited effective treatments or adverse side-effects.
Madhavi Ojha +4 more
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Complete plastome of the medicinally important plant, Alstonia scholaris (Apocynaceae) [PDF]
Mitochondrial DNA. Part B. Resources, 2019 Alstonia scholaris is an evergreen tropical tree with significant medicinal values. To better understand its genetic and genomic profiles, we sequenced and assembled the completed plastome of A. scholaris. The plastome is 154,699 bp in length, consisting
Lei Jin +3 more
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Investigating the Devil's tree (Alstonia scholaris) for its health-safeguarding property and antipathogenic activities against fungi and helminth parasites of veterinary importance [PDF]
Journal of Advanced Veterinary and Animal ResearchObjective: The study was formulated to analyze the health benefits and antifungal and anthelmintic properties of Alstonia scholaris, specifically its bark, as claimed in Mizo traditional medicine.
Lal Ngaihmanawmi +6 more
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Phytochemical Studies on Alstonia scholaris
Zeitschrift Fur Naturforschung - Section B Journal of Chemical Sciences, 2010 Reinvestigation of the flowers of Alstonia scholaris of Pakistan origin have resulted in the isolation of three new triterpenoids, two of the ursane type, 3β -acetate-24-nor-urs-4,12-diene ester triterpene (1) and 3β -hydroxy-24-nor-urs-4,12,28-triene triterpene (2), and one of the oleanane type, 3,28-β - diacetoxy-5-olea-triterpene (3), together with ...
Muhammad Saleem, Nighat Sultana
exaly +2 more sources
Physiochemical screening of road avenue plants in better landscape management of highly polluted urbanized city (Lahore), Pakistan [PDF]
PeerJLahore has been consistently ranked as the world’s most polluted city. Because of combative ideas to construct highways, underpasses and flyovers, Lahore had lost a remarkable percentage of its tree cover over the past 15 years. The present study focuses
Bushra Munam +11 more
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Novel Alkaloids from Alstonia scholaris
Zeitschrift Fur Naturforschung - Section B Journal of Chemical Sciences, 2010 The alkaloidal fraction of Alstonia scholaris leaves shows anti-inflammatory and analgesic bioactivity in vivo. A phytochemical study on this fraction led to the isolation of two novel alkaloids, scholarisine I and (±)-scholarisine II. Their structures were elucidated on the basis of spectroscopic methods, and a possible biogenesis is proposed ...
Tao Feng +2 more
exaly +2 more sources
Acute and Sub-chronic Toxicity of Indole Alkaloids Extract from Leaves of Alstonia scholaris (L.) R. Br. in Beagle Dogs [PDF]
Natural Products and Bioprospecting, 2020 Alstonia scholaris (L.) R. Br., an evergreen tropical plant rich in indole alkaloids with significant physiological activity, is traditionally used to treat respiratory diseases in China.
Yun-Li Zhao +9 more
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Stereochemical insights into sarpagan and akuammiline alkaloid biosynthesis. [PDF]
New PhytolSummary Sarpagan and akuammiline monoterpenoid indole alkaloids (MIAs) are a class of bioactive plant‐derived compounds with significant pharmaceutical potential. These alkaloids are formed through oxidative cyclization of geissoschizine, catalyzed by homologous cytochrome P450 monooxygenases (CYP) known as sarpagan bridge enzymes (SBEs) and rhazimal ...
Mann SGA +6 more
europepmc +2 more sources
Oxidative Rearrangements of the Alkaloid Intermediate Geissoschizine. [PDF]
Angew Chem Int Ed Engl19E‐geissoschizine is a key precursor in the biosynthesis of monoterpene indole alkaloids such as strychnine, ibogaine, and vinblastine. Using enzymatic assays and gene silencing, three CYPs were identified from C. roseus that oxidize this compound to four alkaloid scaffolds: strychnos, sarpagan, akuammiline, and mavacurane. Mutational analysis reveals
Kamileen MO +6 more
europepmc +3 more sources
مجلة علوم ذي قار, 2023 The Indian medical systems hold promise for the genus Alstonia. Different types of Alstonia, primarily Alstonia scholaris, have been used by the various ethnic communities in India to treat various human illnesses.
Alyaa Majid, Hadeel Rashid Faraj
doaj +1 more source