Results 121 to 130 of about 28,483 (297)

Nerinetide Reduces Early Infarct Growth Among Stroke Patients Undergoing EVT Without Intravenous Alteplase

Stroke: Vascular and Interventional Neurology
Background Nerinetide treatment was associated with better clinical outcomes among patients with stroke undergoing endovascular treatment who were not treated with concurrent alteplase in the randomized ESCAPE‐NA1 (Efficacy and Safety of Nerinetide for ...
Nathaniel B. Rex, Johanna M. Ospel, Rosalie V. McDonough, Nima Kashani, Leon A. Rinkel, Brian H. Buck, Jeremy Rempel, Ryan A. McTaggart, Raul G. Nogueira, Alexandre Y. Poppe, Dar Dowlatshahi, Brian A. van Adel, Richard H. Swartz, Ruchir A. Shah, Eric Sauvageau, Andrew M. Demchuk, Michael Tymianski, Michael D. Hill, Mayank Goyal   +18 more
doaj   +1 more source

No relation between body temperature and arterial recanalization at three days in patients with acute ischaemic stroke [PDF]

, 2015
Background: Recanalization of an occluded intracranial artery is influenced by temperature-dependent enzymes, including alteplase. We assessed the relation between body temperature on admission and recanalization.
Bakker, S.L.M. (Stef), Bienfait, H.P. (Henri), Biessels, G.J., Biessels, G.J. (Geert Jan), Boiten, J. (Jelis), Bot, J. (Joseph), Dankbaar, J.W. (Jan), Dijk, E.J. (Ewoud) van, Dippel, D.W.J. (Diederik), Droogh-De Greve, K.E., Duijm, L.E.M. (Lucien), Duyndam, A. (Anita), Geurts, M. (Marjolein), Graaf, Y. (Yolanda) van der, Hofmeijer, J., Horsch, A.D. (Alexander D.), Horsch, A.D. (Alexander D.), Kappelle, L.J., Kappelle, L.J. (Jaap), Keizer, K. (Koos), Kesselring, A.M. (Anouk), Kort, P.L.M. (Paul) de, Kwa, V.I.H., Lugt, A. (Aad) van der, Luitse, J.S.K., Lycklama à Nijeholt, G.J. (Geert), Majoie, C.B. (Charles), Mali, W.P. (Willem), Meijer, F.J. (F.), Niesten, J.M. (Joris), Pleiter, C.C. (C.), Rooij, W.J. (W.) van, Roos, Y.B.W.E.M. (Yvo), Schaaf, I.C. (Irene) van der, Schonewille, W.J. (Wouter), Seeters, T. (Tom) van, Velthuis, B.K. (Birgitta), Visser, M.C. (Marieke), Vos, J.A. (Jan Albert), Walderveen, M.A.A. (Marianne) van, Wermer, M.J.H. (Marieke), Worp, H.B. (Bart) van der   +41 more
core   +1 more source

The resistance of swine blood clots to alteplase-induced thrombolysis in vitro is concentration-dependent

Thrombosis Update, 2021
Background: Swine have been used as a large animal translational research model to investigate the effectiveness of fibrinolytic agents. However, swine thrombi have different characteristics than human thrombi, which may confer more resistance to ...
Evandro M. Neto-Neves, Daren M. Beam, Jeffrey A. Kline   +2 more
doaj  

Uso de trombolíticos e associações farmacológicas no tratamento do acidente vascular cerebral isquêmico agudo : revisão sistemática e meta-análise em rede [PDF]

, 2017
Dissertação (mestrado)—Universidade de Brasília, Faculdade de Ciências da Saúde, Programa de Pós-Graduação em Ciências da Saúde, 2017.Introdução: O acidente vascular cerebral isquêmico (AVCi) é uma das principais causas de mortalidade e incapacidade ...
Brito, Gabriela Vilela de
core  

Association between time to reperfusion and outcome is primarily driven by the time from imaging to reperfusion [PDF]

, 2016
Background and Purpose A progressive decline in the odds of favorable outcome as time to reperfusion increases is well known. However, the impact of specific workflow intervals is not clear.; Methods We studied the mechanical thrombectomy group (n=103 ...
Cerda, Neus, Cobo Valeri, Erik, Dávalos Errando, Antoni, Jovin, Tudor G., Molina, Carlos A., Ribó, Marc, Sanroman, Luis, Tomasello, Alejandro, Urra, Xabier   +8 more
core   +2 more sources

Stroke treatment academic industry roundtable recommendations for individual data pooling analyses in stroke [PDF]

, 2016
Pooled analysis of individual patient data from stroke trials can deliver more precise estimates of treatment effect, enhance power to examine prespecified subgroups, and facilitate exploration of treatment-modifying influences.
Khatri, Pooja, Lees, Kennedy R., STAIR IX Collaborators,   +2 more
core   +1 more source

Early recurrent ischemic stroke complicating intravenous thrombolysis for stroke: incidence and association with atrial fibrillation [PDF]

, 2010
<p><b>Background and Purpose:</b> Mechanisms of early neurologic deterioration after treatment with intravenous, recombinant, tissue-type plasminogen activator (IV rt-PA) include symptomatic intracerebral hemorrhage (SICH) and early ...
Awadh, M., Baird, T., MacDougall, N., Muir, K.W., Santosh, C., Teasdale, E.   +5 more
core   +1 more source

Dual antiplatelet versus alteplase in anterior and posterior circulation minor stroke

Stroke and Vascular Neurology
Objective The Antiplatelet versus R-tPA for Acute Mild Ischaemic Stroke trial has demonstrated the non-inferiority of dual antiplatelet therapy (DAPT) to alteplase in minor non-disabling stroke.
Yu Cui, Hui-Sheng Chen
doaj   +1 more source

Evaluation of an Unfractioned Heparin Pharmacy Dosing Protocol for the Treatment of Venous Thromboembolism in Nonobese, Obese, and Severely Obese Patients [PDF]

, 2017
Background: Despite large interpatient variability in dose response, heparin is utilized for treatment of venous thromboembolism (VTE). Current data on the optimal heparin dosing in obese patients are conflicting. Objective: The objective was to evaluate
Breedlove, Emily Y., Hosch, Lindsey M., Knoderer, Chad A., Scono, Lauren E.   +3 more
core   +2 more sources

Variability and Advancements in ChatGPT Risk of Bias Assessments: A Replication and Comparative Analysis

Journal of Evidence-Based Medicine, Volume 18, Issue 2, June 2025.
Jules Descamps, Matthieu Resche‐Rigon, Guillaume Draznieks, Cesar Quirino, Rémy Nizard, Pierre‐Alban Bouché   +5 more
wiley   +1 more source