Results 101 to 110 of about 20,386 (204)

Effectiveness of alteplase in the very elderly after acute ischemic stroke

Clinical Interventions in Aging, 2013
Josef Yayan Department of Internal Medicine, University Hospital of Saarland, Homburg/Saar, Germany Abstract: Alteplase has traditionally been the only pharmacologic agent available for treating acute ischemic stroke worldwide, and is considered an ...
Yayan J
doaj  

Analysis of hemorrhagic transformation and intracerebral hemorrhage under combination therapy with alteplase and antiplatelets or anticoagulants, using the Japanese Adverse Drug Event Report database.

PLoS ONE
Recombinant tissue-type plasminogen activators (rtPA) effectively dissolve blood clots and improve symptoms in patients with acute ischemic stroke and myocardial infraction.
Tsuyoshi Nakai, Takenao Koseki, Hiroka Nakao, Koki Kato, Kazuo Takahashi, Shigeki Yamada, Shoji Matsumoto   +6 more
doaj   +1 more source

The use of thrombolytics in the management of complex pleural fluid collections [PDF]

, 2017
Bahjri, Khaled, Copeland, Hannah, Duldulao, Marjulin, Heimes, Jessica, Lulla, Aditya, Wallen, Jason M, Zaheer, Salman   +6 more
core   +2 more sources

Comparative Efficacy and Safety of Different Tenecteplase Doses With Alteplase in Acute Ischemic Stroke: A Systematic Review With Pairwise and Network Meta‐Analysis to Determine the Optimal Dose

Brain and Behavior
Background: Tenecteplase (TNK) is a novel thrombolytic agent gaining attention as an alternative to alteplase for treating acute ischemic stroke (AIS).
Muhammad Hassan Waseem, Zain ul Abideen, Muhammad Haris Khan, Muhammad Fawad Tahir, Marium Khan, Hafsa Arshad Azam Raja, Ameer Haider Cheema, Sania Aimen, Muhammad Arslan Tariq, Javed Iqbal   +9 more
doaj   +1 more source

Risk of angioedema and thrombolytic therapy among stroke patients: An analysis of data from the FDA Adverse Event Reporting System database

Neurotherapeutics
The angioedema risk may vary among stroke patients receiving different thrombolytic agents. This study aimed to investigate the angioedema risk associated with different thrombolytic agents and to identify associated risk factors.
Hunong Xiang, Yu Ma, Xiaochao Luo, Jian Guo, Minghong Yao, Yanmei Liu, Ke Deng, Xin Sun, Ling Li   +8 more
doaj   +1 more source

Tenecteplase versus alteplase in patients with acute ischemic stroke: an updated systematic review and meta-analysis

European Journal of Medical Research
Background Stroke was the second leading cause of death and the third leading cause of disability worldwide in 2019. Alteplase is an FDA-approved medication for the treatment of patients with ischemic stroke within 4.5 h.
Abdelmonam M. Hagag, Muhammed E. Kormod, Mahmoud Elmwafy Ads, Mennatullah A. El-Refaay, Omnia M. Abozaid, Omar A. Ghanem, Mazen Yasser, Karim M. Abdelmoaty, Alaa Mahmoud Khedr, Gregory W. Albers   +9 more
doaj   +1 more source

Implementation of a Tenecteplase Protocol for Treatment of Acute Ischemic Stroke in a Health System

INNOVATIONS in Pharmacy
Purpose. Alteplase is the standard of care for intravenous thrombolytic treatment of acute ischemic stroke, but recent evidence suggests that tenecteplase may be as safe and efficacious. The purpose of this study was to evaluate the direct cost savings,
Alexis Pace, Maya Wai, Ethan Frye
doaj  

Clinical experience with alteplase in the management of intracardiac and major cardiac vessels thrombosis in pediatrics: a case series

Annals of Saudi Medicine, 2010
Background and Objectives: Experience with alteplase in pediatric patients is limited and recommendations are extrapolated from adult data. Comprehensive guidelines on the management of thromboembolic events in this group are lacking.
Al-Jazairi Abdulrazaq, Al-Gain Roaa, Bulbul Zead, Cherfan Antoine   +3 more
doaj  

Diagnosis and management of transient ischaemic attack and ischaemic stroke in the acute phase [PDF]

, 2011
Dawson, J., McArthur, K.S., Quinn, T.J., Walters, M.R.   +3 more
core   +1 more source

Comparison of the efficacy and safety of different thrombolytic drugs in the treatment of acute ischemic stroke within 4.5 h: a systematic review and network meta-analysis. [PDF]

Front Neurol
Yu X, Liu J, Shi C, Xue D, Jiang Y, Wang W, Zhao M.   +6 more
europepmc   +1 more source