Results 81 to 90 of about 20,386 (204)

Revisiting Incomplete Tissue‐Level Reperfusion Following Successful Thrombectomy for Acute Ischemic Stroke

Annals of Neurology, Volume 99, Issue 3, Page 668-683, March 2026.
[Color figure can be viewed at www.annalsofneurology.org] Among patients with acute ischemic stroke achieving successful large vessel recanalization (defined as expanded Thrombolysis in Cerebral Infarction [eTICI ≥2b]), incomplete tissue‐level reperfusion, distinct from visually identifiable distal occlusion on digital‐subtraction angiography, remains ...
Yue Qiao, Adrien Ter Schiphorst, Yi Xu, Jean‐Claude Baron, Wenbo Zhao   +4 more
wiley   +1 more source

Eficacia y seguridad del tenecteplase en el tratamiento del ACV isquémico agudo

Acta Neurológica Colombiana, 2020
El alteplase es el único fibrinolítico actualmente autorizado en Colombia para el tratamiento del ACV isquémico agudo. El tenecteplase constituye una nueva alternativa de tratamiento en esta enfermedad al ofrecer mejor perfil farmacológico, mayor ...
Javier Francisco Torres Zafra, Germán Enrique Pérrez Romero   +1 more
doaj   +1 more source

Comparison of the National Institutes of Health Stroke Scale with disability outcome measures in acute stroke trials [PDF]

, 2005
<p><b>Background and Purpose:</b> Acute stroke trials typically use disability scales as their primary end point. Neurologic impairment scales such as the National Institutes of Health Stroke Scale (NIHSS) are possibly more sensitive to
Lees, K.R., Weir, C.J., Young, F.B.
core   +1 more source

The Role of Extracellular Vesicles in Transient Ischaemic Attacks and Ischaemic Stroke: A Systematic Review

Journal of Extracellular Biology, Volume 5, Issue 3, March 2026.
Both transient ischaemic attack (TIA) and ischaemic stroke lead to an increase in individual cellular‐derived populations of extracellular vesicles (EVs), including endothelial, platelet and leukocyte derived. These EVs have downstream roles in the pathophysiological events associated with TIA and stroke, including dysregulated inflammation and ...
Rebecca Marie Raven, Philip Eurig James, Keith Morris, Jessica Olivia Williams   +3 more
wiley   +1 more source

Coronary flow and hemorrhagic complications after alteplase and streptokinase administration in patients with acute myocardial infarction [PDF]

, 2009
Background/Aim. Up-to-date treatment of acute myocardial infarction (AIM) has been based on as early as possible establishment of circulation in ischemic myocardium whether by the use of fibrinolythic therapy and/or urgent coronary intervention which ...
Apostolović Svetlana, Božinović Nenad, Kostić Tomislav, Milić Dragan, Mitov Vladimir, Perišić Zoran, Vidanović Miroslav, Šalinger-Martinović Sonja   +7 more
core   +1 more source

Intravenous tenecteplase compared with alteplase for minor ischaemic stroke: a secondary analysis of the AcT randomised clinical trial

Stroke and Vascular Neurology
Background In ischaemic stroke, minor deficits (National Institutes of Health Stroke Scale (NIHSS) ≤5) at presentation are common but often progress, leaving patients with significant disability.
Dar Dowlatshahi, Mohammed A Almekhlafi, Tolulope Sajobi, Aleksandra Pikula, Ashfaq Shuaib, Alexandre Y Poppe, Richard H Swartz, Fouzi Bala, Ibrahim Alhabli, Aleksander Tkach, Heather Williams, Shelagh B Coutts, Nishita Singh, Anurag Trivedi, Andrew Demchuk, Gary Hunter, Brian H Buck, Faysal Benali, Bijoy Menon, MacKenzie Horn, Radhika Nair, Thalia Field, Mahesh Kate, Negar Asdaghi, Robert Sarmiento, Ayoola Ademola, Houman Khosravani, Herbert Alejandro Manosalva Alzate, Luciana Catanese   +28 more
doaj   +1 more source

Can the ischemic penumbra be identified on noncontrast CT of acute stroke? [PDF]

, 2007
<p><b>Background and Purpose:</b> Early ischemic changes on noncontrast CT in acute stroke include both hypoattenuation and brain swelling, which may have different pathophysiological significance.</p> <p><b>Methods:
Baird, T., Baird-Gunning, J., Coutts, S.B., McCormick, M., Muir, K.W., Walker, L.   +5 more
core   +1 more source

Predictors of the unfavorable outcomes in acute ischemic stroke patients treated with alteplase, a multi-center randomized trial

Scientific Reports
Worldwide, stroke is a leading cause of long-term disability in adults. Alteplase is the only approved treatment for acute ischemic stroke (AIS) and results in an improvement in a third of treated patients.
Mohamed G. Zeinhom, Mohamed Fouad Elsayed Khalil, Islam Fathallah Mohamed Kamel, Ahmed Mohamed Kohail, Sherihan Rezk Ahmed, Ahmed Elbassiouny, Ashfaq Shuaib, Omar M Al-Nozha   +7 more
doaj   +1 more source

Timing of vessel imaging for suspected large vessel occlusions does not affect groin puncture time in transfer patients with stroke. [PDF]

, 2018
BACKGROUND: Access to endovascular therapy (ET) in cases of acute ischemic stroke may be limited, and rapid transfer of eligible patients to hospitals with endovascular capability is needed.
Dhamoon, Mandip S., Fifi, Johanna T., Liang, John W., Stein, Laura, Tuhrim, Stanley, Wilson, Natalie   +5 more
core   +1 more source

Alteplase in COVID-19 severe hypoxemic respiratory failure: the TRISTARDS multicenter randomized trial

Annals of Intensive Care
Background Pulmonary intravascular thrombus formation has been widely observed in patients with respiratory failure, for example, in patients with SARS-CoV-2 infection (COVID-19).
Giovanni Landoni, Pratima Chowdary, Ferhat Meziani, Jacques Creteur, Nicolas De Schryver, Johann Motsch, Ingrid Henrichmoeller, Alain Pagès, Nuala Peter, Thierry Danays, Markus A. Weigand, the TRISTARDS Investigators   +11 more
doaj   +1 more source