Results 61 to 70 of about 10,399 (159)

Predicting the safety of intravenous thrombolysis with Fortelyzin in patients over 60 years of age with ischemic stroke using the THRIVE scale

Неврология, нейропсихиатрия, психосоматика
Objective: to evaluate the prognostic value of the THRIVE scale in patients aged 60 years and older with ischemic stroke (IS) after intravenous thrombolysis with Fortelyzin® (INN/chemical name – recombinant protein containing the amino acid sequence of ...
N. A. Shamalov, M. Yu. Martynov, E. B. Yarovaya, V. A. Kutsenko, N. A. Marskaya, Zh. Yu. Chefranova, A. M. Semenov, M. P. Semenov, S. V. Ivanov, М. К. Guseva, Е. А. Karpova, Yu. A. Romashova, V. V. Beregovykh, S. S. Markin   +13 more
doaj   +1 more source

Dual antiplatelet versus alteplase in anterior and posterior circulation minor stroke

Stroke and Vascular Neurology
Objective The Antiplatelet versus R-tPA for Acute Mild Ischaemic Stroke trial has demonstrated the non-inferiority of dual antiplatelet therapy (DAPT) to alteplase in minor non-disabling stroke.
Yu Cui, Hui-Sheng Chen
doaj   +1 more source

Lingual angioedema with macroglossia during the treatment of acute ischemic stroke with alteplase

International Journal of General Medicine, 2012
Josef YayanDepartment of Internal Medicine, Vinzentius-Hospital, Landau, GermanyAbstract: Alteplase (recombinant tissue plasminogen activator) has been used in the treatment of acute ischemic stroke for 10 years.
Yayan J
doaj  

Effectiveness of alteplase in the very elderly after acute ischemic stroke

Clinical Interventions in Aging, 2013
Josef Yayan Department of Internal Medicine, University Hospital of Saarland, Homburg/Saar, Germany Abstract: Alteplase has traditionally been the only pharmacologic agent available for treating acute ischemic stroke worldwide, and is considered an ...
Yayan J
doaj  

Effect of concomitant usage of alteplase and mechanical thrombectomy for M1 middle cerebral artery occlusion on clinical outcome: a retrospective analysis of 457 patients from two centers

Frontiers in Neurology
IntroductionEndovascular thrombectomy (EVT) and concomitant usage of intravenous alteplase (alteplase) in large vessel occlusion stroke may produce unwanted excess intracerebral hemorrhage (ICH). Whether this applies specifically to isolated occlusion of
Slaven Pikija, Monika Killer-Oberpfalzer, Monika Killer-Oberpfalzer, Johannes A. R. Pfaff, Christoph J. Griessenauer, Michael Sonnberger, Milan Vosko, Johannes S. Mutzenbach, Daniel Schwarzenhofer, Constantin Hecker, Constantin Hecker   +10 more
doaj   +1 more source

Comparative effectiveness and safety of tenecteplase versus alteplase for intravenous thrombolysis in acute ischemic stroke: a retrospective study

Frontiers in Neurology
BackgroundTenecteplase has been proposed as a practical alternative to alteplase for intravenous thrombolysis in acute ischemic stroke. Although randomised trials have demonstrated noninferiority, data from real-world comparative cohorts remain limited ...
Weili Zhao, Xi Zhang, Yang Zhao, Ruijie Zhao, Yalin Liu   +4 more
doaj   +1 more source

Comparative Efficacy and Safety of Different Tenecteplase Doses With Alteplase in Acute Ischemic Stroke: A Systematic Review With Pairwise and Network Meta‐Analysis to Determine the Optimal Dose

Brain and Behavior
Background: Tenecteplase (TNK) is a novel thrombolytic agent gaining attention as an alternative to alteplase for treating acute ischemic stroke (AIS).
Muhammad Hassan Waseem, Zain ul Abideen, Muhammad Haris Khan, Muhammad Fawad Tahir, Marium Khan, Hafsa Arshad Azam Raja, Ameer Haider Cheema, Sania Aimen, Muhammad Arslan Tariq, Javed Iqbal   +9 more
doaj   +1 more source

Analysis of hemorrhagic transformation and intracerebral hemorrhage under combination therapy with alteplase and antiplatelets or anticoagulants, using the Japanese Adverse Drug Event Report database.

PLoS ONE
Recombinant tissue-type plasminogen activators (rtPA) effectively dissolve blood clots and improve symptoms in patients with acute ischemic stroke and myocardial infraction.
Tsuyoshi Nakai, Takenao Koseki, Hiroka Nakao, Koki Kato, Kazuo Takahashi, Shigeki Yamada, Shoji Matsumoto   +6 more
doaj   +1 more source

Implementation of a Tenecteplase Protocol for Treatment of Acute Ischemic Stroke in a Health System

INNOVATIONS in Pharmacy
Purpose. Alteplase is the standard of care for intravenous thrombolytic treatment of acute ischemic stroke, but recent evidence suggests that tenecteplase may be as safe and efficacious. The purpose of this study was to evaluate the direct cost savings,
Alexis Pace, Maya Wai, Ethan Frye
doaj  

Early Reperfusion in Basilar Artery Occlusion Stroke Managed With Tenecteplase Versus Alteplase Before Endovascular Treatment. [PDF]

Stroke Vasc Interv Neurol
Wolman DN, Karamchandani RR, Darko K, Bielinski TM, Goyal N, Rhoten JB, Jayaraman MV, Sidebottom CT, Gross BA, Al-Bayati AR, Doheim MF, Tobin MK, Chinthala A, Gajjar A, Mascitelli J, Webb MR, Burkhardt JK, Scott KW, Srinivasan V, Tonetti D, Koneru M, Altschul DJ, Vaishnav D, Multani S, Theofanis T, Ares WJ, Sone JY, Zand R, Bahrami S, Li J, Defilipp G, Strong D, Torabi R, Moldovan K, Schirmer CM, Nogueira RG, Bohnstedt BN, Paul AR, Hendrix P.   +38 more
europepmc   +1 more source