Results 191 to 200 of about 57,547 (311)

Central Involvement in Pure Autonomic Failure: Insights from Neuromelanin-Sensitive Magnetic Resonance Imaging and ¹⁸F-Fluorodopa-Positron Emission Tomography. [PDF]

Mov Disord
Trujillo P, O'Rourke KR, Roman OC, Song AK, Hett K, Cooper A, Black BK, Donahue MJ, Shibao CA, Biaggioni I, Claassen DO.   +10 more
europepmc   +1 more source

Béatrice Longuenesse: Hegel’s Critique of Metaphysics [PDF]

, 2012
Yeomans, Christopher
core  

Alteration

The International Journal of Whole Person Care, 2022
openaire   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

'Why Bother?' Skeptical Doubt and Moral Imagination in Care for People with Profound Intellectual Disabilities. [PDF]

Cult Med Psychiatry
van der Weele S.
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Bibliotherapy and Schizophrenia: A Stanghellinian Perspective.

Psychopathology
Delcourt F, Englebert J, Pachoud B.
europepmc   +1 more source

The Wide Reach of Salvation: Christian Universalism in the Novels of Denise Giardina

, 2016
Jolliff, William
core  

Rejoining Alētheia and Truth: or Truth Is a Five-Letter Word [PDF]

, 1990
Hatab, Lawrence J.
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source