Results 111 to 120 of about 2,129 (272)

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source

WPEye.net: An Alternate Reality Game for WPI Admissions

, 2008
One of WPI's long term goals is to increase the enrollment rate of accepted students. The goal of this project is to continue the work of a previous IQP to investigate the viability of alternate reality games as a marketing tool for university enrollment
Corfman, Daniel Philip, Lampke, Sarah F., Cotnoir, Joseph D., Volpe, Timothy J., Hickcox, Andrew Stevens   +4 more
core  

Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

Advanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source

Motivation in alternate reality gaming environments and implications for learning

, 2009
Alternate Reality Games are being used increasingly in Higher Education as a way of providing a stimulating context for student learning. However, several instances have shown that students are not as motivated to take part in this type of active ...
Alex Moseley (7596206), Katie Piatt (7596212), Juliette Culver (7596209), Nicola Whitton (4781925)   +3 more
core  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Marketing and Mystery : Analysis and Evaluation of the Viral Marketing Concept “Alternate Reality Game” using the Example of Cloverfield

, 2012
In dieser Arbeit wird das neuartige Konzept der „Alternate Reality Games“ als Mittel des viralen Marketings analysiert. Nach einer Einführung in den Aufbau und die Natur von „Alternate Reality Games“ im Allgemeinen wird am Beispiel der Hollywood ...
Godenrath, Sven
core  

MFPD: A Multiple Fungal Pathogen Detection Pipeline Across Diverse Habitats

Advanced Science, EarlyView.
The MFPD pipeline integrates a comprehensive ITS reference database of fungal pathogens, optimized parameters, and algorithms tailored for both full‐length and subregion sequences that balance accuracy and computational efficiency; it enables high‐throughput, species‐level identification from amplicon sequencing data, supporting large‐scale ...
Yi Shen, Xinrun Yang, Jiabao Yu, Yaozhong Zhang, Tianjie Yang, Yang Gao, Xiaofang Wang, Alexandre Jousset, Waseem Raza, Fang‐Jie Zhao, Qirong Shen, Gaofei Jiang, Zhong Wei, Yangchun Xu   +13 more
wiley   +1 more source

Jumping through the layers: alternate reality games and literature

, 2012
"Imagine this: Tomorrow morning, you check your email as you always do, and you see you‘ve received a puzzling message from an unfamiliar sender. The email, when you open it, tells you the beginning of a story in which a shy student named Ana, (searching
Barrios-O'Neill, Danielle, Hook, Alan
core  

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Effectiveness of various dosage parameters of Wii Fit Plus exergames for enhancing balance and postural control among people post-stroke: a systematic review protocol. [PDF]

JBI Evid Synth
Pratihar S, Rajasekaran K, Janakiraman B.   +2 more
europepmc   +1 more source