Results 131 to 140 of about 2,129 (272)

More than a game: Examining sensemaking and self-organisation in alternate reality games

open access: yes, 2014
Alternate Reality Games (ARGs) are an emerging brand of online role-playing games, immersive and highly interactive. This new genre of games pioneered an effective and efficient form of collective play and problem-solving in loosely-defined situations ...
Alanna, Yeo Yun Ting
core  

ACLY‐Driven Metabolic Reprogramming Promotes Histone Acetylation and Inflammation‐Associated Fibrosis in Chronic Kidney Disease

open access: yesAdvanced Science, EarlyView.
This study reveals a citrate–ACLY–H3K27ac metabolic–epigenetic axis driving inflammatory gene activation and kidney fibrosis, highlighting ACLY inhibition as a potential therapeutic strategy for chronic kidney disease (CKD). ABSTRACT The mechanisms by which metabolic stress drives epigenetic dysregulation and fibrosis in chronic kidney disease (CKD ...
Chunxiu Du   +15 more
wiley   +1 more source

ARG (Alternate Reality Games). Contributions, Limitations, and Potentialities to the Service of the Teaching at the University Level

open access: yes, 2014
Education’s gamification has represented an opportunity to boost students’ interaction, motivation and participation. ARG (Alternate Reality Games) offer a new highly immersive tool that can be implemented in educational achievements.
Otero, Teresa, Sánchez, Carmen
core  

Mechanically Triggered DNA Nanovehicles for Targeted Dual‐Drug Cancer Therapy

open access: yesAdvanced Science, EarlyView.
A mechanically triggered DNA nanovehicle is introduced that co‐releases two anticancer drugs in response to integrin‐mediated cellular forces. Cholesterol‐anchored DNA assemblies undergo force‐induced unfolding at cell–cell junctions, enabling selective, localized dual‐drug activation in cancer cells while minimizing off‐target toxicity in low‐tension ...
Murali Mohana Rao Singuru   +2 more
wiley   +1 more source

Patient input on the design of a social virtual reality environment for hospitalized older adult trauma patients: Phase 1 of a usability, acceptability, and feasibility pilot study. [PDF]

open access: yesDigit Health
McLeod Daphnis SI   +11 more
europepmc   +1 more source

Leveling-Up With Cultural Heritage : Aspects from Gamification and Alternate Reality Games

open access: yes, 2015
This thesis explores how heritage museums can engage more visitors to take part of cultural heritage in context to digital culture, and going deeper in on what implementation of gamification and alternate reality games can contribute with.
Salomonsson, Lisa
core  

Dumbbell‐Structured Plasmonic‐Enhanced Optical Nanoprobes Boosting Photo‐Magnetic‐Acoustic Multimodal Imaging‐Guided Photodynamic‐Photothermal Synergistic Treatment and Immunogenic Death in Nasopharyngeal Carcinoma

open access: yesAdvanced Science, EarlyView.
This study reports a novel rationally‐designed optical nanoprobe based on dumbbell‐shaped mesoporous silica‐coated gold nanorods, loaded with rare‐earth oxides, photosensitizers, and tumor‐targeted peptides, enabling plasmonic‐enhanced multimodal imaging and PTT‐PDT synergy.
Baikang Zhuang   +12 more
wiley   +1 more source

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