Results 141 to 150 of about 2,129 (272)

Alternate and Immanent Critiques: Collectivities and Serious Gaming in Alternate Reality Games

, 2009
This paper was presented at Paper Session 6b: Resistance and Activism.
openaire   +1 more source

Narrative friction in Alternate Reality Games: Design insights from conspiracy for good.

, 2011
Alternate Reality Games (ARG) tend to have story-driven game structures. Hence, it isuseful to investigate how player activities interact with the often pre-scripted storyline inthis genre.
Markus Montola (17922113), Annika Waern (5392061), Elina Ollila (17922119), Jussi Holopainen (17160103), Jaakko Stenros (7550464)   +4 more
core  

Drug‐Induced Cuproptosis Defines the Therapeutic Window of Celecoxib in Intervertebral Disc Degeneration via the HSP90‐RBX1 Axis

Advanced Science, EarlyView.
This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo, Hongju Xiao, Shenghao Ba, Yu Zhou, Bijun Wang, Bin Yu, Yufeng Huang, Haihong Zhao, Zhefan Stephen Chen, Na Shen, Zhaoyu Ba, Desheng Wu   +11 more
wiley   +1 more source

Application of Digital, Web-Based, and Online Strategies in Point of Care Ultrasound (POCUS) Training: A Scoping Review. [PDF]

Health Sci Rep
Hang J, Maranna S, Parange N, Kumar S.
europepmc   +1 more source

Wireless, Deep‐Seeing Smart Pill: A NIR‐II Fluorescence Imaging Capsule Endoscope for Gastrointestinal Cancer

Advanced Science, EarlyView.
A novel near‐infrared‐II fluorescent imaging capsule endoscope that detects specific fluorescence signals above 900 nm enables highly sensitive, targeted imaging of gastrointestinal cancer tissue. This wirelessly powered and magnetically controlled “smart pill” achieves high sensitivity and deep tissue penetration, allowing precise, non‐invasive ...
Weicheng Wang, Jinlei Jiang, Zhengting Wang, Shuqi Liu, Wei Wang, Xi Chen, Qirui Zhao, Xinyuan Cui, Cheng Zhou, Shengsheng Cui, Daxiang Cui   +10 more
wiley   +1 more source

Counterclockwise Virtual Reality-Based Embodiment of a Younger Self and Revisit of a Past Iconic Event in Older Adults: Between-Groups Study of Cognitive and Physical Performance. [PDF]

JMIR Form Res
Banakou D, Itatani R, Montserrat R, Porta-Mas C, Bartrés-Faz D, Bodner E, Mataro M, Slater M.   +7 more
europepmc   +1 more source

“Membrane‐Guided” Repair Strategy: Precision Delivery of GGT1 Degrader for Targeted Repair and Regeneration of Spinal Cord Neurons

Advanced Science, EarlyView.
This study confirms that GGT1 is a key driver of neuronal ferroptosis following spinal cord injury. We developed NSCm@EA, a biomimetic delivery system coated with neural stem cell membranes, for precise delivery of enocyanin to injured neurons. By combining targeted delivery with ubiquitination degradation mechanisms, this system promotes MGRN1 ...
Tao Yang, Lei Ye, Peigen Xie, Tao Song, Jian Chen, Heng Zhao, Zhengshan Liu, Xi Chen, Jianing Ding, Xintian Ding, Ao Shao, Miaomiao Wu, Fengdong Zhao, Siyue Tao, Tao You   +14 more
wiley   +1 more source

Gamification Strategies in Undergraduate Nursing Education: A Systematic Review Protocol. [PDF]

Nurs Rep
Elia RA, Colangelo M, Cerrone V, Pace D, Andretta V.   +4 more
europepmc   +1 more source

Stress‐to‐Light Conversion in an Earth‐Abundant Oxide Semiconductor

Advanced Science, EarlyView.
Stress‐to‐light conversion in solids represents a unique photonic functionality, yet it has never been realized in a chemically simple and sustainable material. Here, we show that sustainable semiconductor ZnO exhibits strong near‐infrared (NIR) luminescence under elastic stress when defect‐engineered to stabilize the p‐type state.
Tomoki Uchiyama, Koki Otonari, Reona Omori, Guangfa Yang, Eiji Nishibori, Ying Chen, Xu‐Guang Zheng, Chao‐Nan Xu   +7 more
wiley   +1 more source

Adaptive VR intervention on social-cognitive skills in children with ASD: a feasibility study. [PDF]

Int J Clin Health Psychol
Maddalon L, Altozano A, Minissi ME, Marín-Morales J, Romero GL, Parsons T, Hervás A, Alcañiz M.   +7 more
europepmc   +1 more source