Results 101 to 110 of about 24,387,293 (346)
Members of the miR‐200 family are critical gatekeepers of the epithelial state, restraining expression of pro‐mesenchymal genes that drive epithelial–mesenchymal transition (EMT) and contribute to metastatic cancer progression.
Katherine A. Pillman +20 more
semanticscholar +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Multi-criteria decision analysis (MCDA) for control of transboundary livestock diseases using the example of the 2010/11 foot-and-mouth disease (FMD) outbreak in the Republic of Korea : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Science at Massey University, Manawatū [PDF]
Decisions regarding transboundary livestock disease control strategies differ from personal decisions, such as buying groceries, in important ways: the stakes are high and the outcome of a decision will affect people in different fields.
Kim, EuTteum
core
Biofilm Control: Conventional and Alternative Approaches [PDF]
“Biofouling” is referred to as the unwanted deposition and growth of biofilms. This phenomenon can occur in an extremely wide range of opportunities ranging from colonization of medical devices, during production of ultrapure drinking and process water, and fouling of ship hulls, pipelines and reservoirs.
Flemming, Hans-Curt, Ridgway, Harry
openaire +2 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Some essential oils are rich in nematicidal compounds and can be used for the management of plant-parasitic nematodes. Laboratory and field studies aiming to evaluate the efficiency of this compounds are necessary.
Darlan Ferreira Borges +5 more
doaj +1 more source
A spatial accuracy assessment of an alternative circular scan method for Kulldorff's spatial scan statistic [PDF]
This paper concerns the Bernoulli version of Kulldorff’s spatial scan statistic, and how accurately it identifies the exact centre of approximately circular regions of increased spatial density in point data. We present an alternative method of selecting
Bath, P.A. +3 more
core
Alternatives to the Randomized Controlled Trial
Public health researchers are addressing new research questions (e.g., effects of environmental tobacco smoke, Hurricane Katrina) for which the randomized controlled trial (RCT) may not be a feasible option. Drawing on the potential outcomes framework (Rubin Causal Model) and Campbellian perspectives, we consider alternative research ...
Stephen G, West +10 more
openaire +3 more sources
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source

