The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Economics of Alternative Crop Production in Arid Regions [PDF]
As water resources in arid regions decline, agricultural producers are encouraged to adopt water conserving strategies. The implementation of alternative low-water use crops is one option, but is it economically feasible?
Bishop, Carol +2 more
core +1 more source
Environmental Impacts of Diverting Crop Residues to Fuel Use [PDF]
, 1997 Shortage of fuel wood has lead many rural people to switch to using agricultural residues as an alternative energy source. However this has not always been met with universal acclaim due to the role of residues as fertilisers.
Clancy, J.
core +1 more source
Effect of Plant Growth-Promoting Rhizobacteria on Salicornia ramosissima Seed Germination under Salinity, CO2 and Temperature Stress [PDF]
, 2019 In a scenario of climate change and growing population, halophyte root microbiota interactions may be a sustainable solution to improve alternative crop production while combating abiotic stress.
Bernabeu Meana, Miguel +6 more
core +1 more source
Crop-Cattle Integrated Farming System: An Alternative of Climatic Change Mitigation
Media Peternakan, 2015 An integrated farming system is one of the alternatives for climatic change mitigation. This paper reports the application of corn-cattle based integrated farming system in Agrotechno Park Center of Palembang, and discusses its impact on CO2 fixation and
Munandar +4 more
doaj +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Correction of Measurement Error in Monthly USDA Pig Crop: Generating Alternative Data Series [PDF]
The imputed pig death loss contained in the reported monthly U.S. Department of Agriculture (USDA) pig crop data over the December 1995–June 2006 period ranged from 24.93% to 12.75%.
Bullock, J. Bruce +3 more
core +1 more source
Possible alternatives in crop nutrition
Acta Agraria Debreceniensis, 2011 The protection of the environment is our common task. All pollution that exposes our soils, plants or the environment – as taken in any proper or extended sense – will appear sooner or later in the food chain and in human beings who are on the top of the food-chain pyramid.
openaire +2 more sources
Pig slurry as an alternative to mineral fertilizer in maize crop
Semina: Ciências Agrárias, 2014 The use of swine residue (SR) as a source of nutrients in growing crops such as maize, may be an option for disposal of organic waste produced in large quantities in pig farms, allowing total or partial substitution of mineral fertilizer in agricultural ...
Moacir Tuzzin de Moraes +5 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source