Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Stevia as an alternative crop for tobacco production in RN Macedonia [PDF]
Ratarstvo i PovrtarstvoThe reform of the Common Agricultural Policy (CAP) for the tobacco sector in the European Union aims to gradually phase out subsidies for tobacco cultivation, a change that will significantly impact the tobacco industry in the Republic of North Macedonia.
Dimov Zoran, Iljovski Igor, Canev Ile
doaj +1 more source
Transgenic oilseed crops as an alternative to fish oils
Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA), 2011 Growing evidence suggests that omega-3 long chain polyunsaturated fatty acids (VLC-PUFAs), especially eicosapentaenoic acid (EPA; 20:5Δ5,8,11,14,17) and docosahexaenoic acid (DHA; 22:6Δ4,7,10,13,16,19) play critical roles in human health and development. VLC-PUFAs are mainly found in fish, some fungi, marine bacteria and microalgae.
Sayanova, O. V., Napier, J. A.
openaire +2 more sources
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Pitaya as a New Alternative Crop for Iberian Peninsula: Biology and Edaphoclimatic Requirements. [PDF]
Plants (Basel), 2023 Trindade AR +5 more
europepmc +1 more source
Saffron, An Alternative Crop for Sustainable Agricultural Systems: A Review
Agronomy for Sustainable Development, 2008 Saffron (Crocus sativus L.) is an autumnal flowering geophite whose dried stigmas, well known for their aromatic and colouring power, have been used since immemorial time as a spice in human nutrition, for medicinal purposes and as a dye. Many doubts remain on its origin; it was probably selected and domesticated in Crete during the Late Bronze Age ...
Gresta F +3 more
openaire +9 more sources
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Procedimientos para Cosechar Lúpulos en Producción a Pequeña Escala
EDIS, 2022 Este artículo explica los procedimientos de cosecha de lúpulo para la producción a pequeña escala (generalmente hasta 5 acres). Este artículo es parte de una serie que examina los desafíos y las oportunidades para la producción de lúpulo en Florida con ...
Shinsuke Agehara +5 more
doaj
ECOLOGICAL AND ECONOMIC CONFLICTS: AGRICULTURAL USE OR CULTIVATION BIOMASS SECOND GENERATION
Вісник Київського національного університету імені Тараса Шевченка. Серія Економіка, 2014 To negotiate the consequences of agricultural modernization as an example of nature Polissya areas in Ukraine. Studies addressing the conceptual foundations of ecological and economic conflict over agricultural use or cultivation of second generation ...
T. Trohlyuk
doaj +1 more source
Industrial hemp (Cannabis sativa L.)-a valuable alternative crop for growing in agricultural soils contaminated with heavy metals. [PDF]
Environ Sci Pollut Res Int, 2023 Flajšman M +4 more
europepmc +1 more source