Results 61 to 70 of about 4,440,446 (253)

Uncovering the transcriptional control of "Bartonella henselae" host adaptation factors [PDF]

open access: yes, 2014
A recurrent theme in bacterial pathogenicity is the understanding of the regulatory events necessary for a given pathogen to progress through its infection cycle while resisting the host defense mechanisms.
Québatte, Maxime
core   +1 more source

Tetrahymena: an alternative model host for evaluating virulence of Aeromonas strains. [PDF]

open access: yesPLoS ONE, 2012
An easier assessment model would be helpful for high-throughput screening of Aeromonas virulence. The previous study indicated the potential of Tetrahymena as a permissive model to examine virulence of Aeromonas hydrophila.
Mao-Da Pang   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Diet quality determines interspecific parasite interactions in host populations [PDF]

open access: yes, 2014
The widespread occurrence of multiple infections and the often vast range of nutritional resources for their hosts allow that interspecific parasite interactions in natural host populations might be determined by host diet quality. Nevertheless, the role
Lange, B.   +8 more
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Host Restaurant Menu 2020 [PDF]

open access: yes, 2020
Host is like a chink of a much more cosmopolitan city shining through the suburban Dublin village of Ranelagh. They follow the winning neighbourhood formula of sharing plates, natural wine and sharply dressed staff, but the handmade pasta and general ...
Restaurant, Host
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Alternative hosts of banana bunchy top virus in the Philippines and the first evidence of seed transmission of BBTV

open access: yesFrontiers in Plant Science
Banana bunchy top disease is caused by banana bunchy top virus (BBTV). BBTV is transmitted locally by aphids (Pentalonia spp.), but the long-distance spread is through the movement of infected planting materials.
Nicole Angelee P. Mendoza   +3 more
doaj   +1 more source

Mass Tourism vs Alternative Tourism? Challenges and New Positionings

open access: yesÉtudes Caribéennes, 2015
Mass tourism is part of a historical construction. It has emerged on the day after the Second World War with sustained economic growth provided by Western countries.
Sopheap Theng, Xiao Qiong, Corina Tatar
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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