Results 101 to 110 of about 17,755,012 (348)
Agro@mbiente On-line, 2016 The incorporation of organic material together with with the addition of an antagonist may enable control of soil-borne pathogens which are difficult to eradicate, resulting in improvements in the physical, chemical and biological characteristics of the ...
Joacy Fonsêca Neto +5 more
doaj +1 more source
Learning objects and learning designs: an integrated system for reusable, adaptive and shareable learning content [PDF]
, 2005 This paper proposes a system, the Smart Learning Design Framework, designed to support the development of pedagogically sound learning material within an integrated, platform-independent data structure.
Agostinho +5 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Incorporation of Brazilian Diatomite in the Synthesis of An MFI Zeolite
Molecules, 2019 The need for greener procedures is a fact to reduce residues, to decrease industrial costs, and to accomplish the environmental agreements. In an attempt to address this question, we propose the addition of a natural resource, Brazilian diatomite, to an ...
Paloma Vinaches +6 more
doaj +1 more source
Discrete Hubbard-Stratonovich transformations for systems with orbital degeneracy
, 1997 A discrete Hubbard-Stratonovich transformation is presented for systems with an orbital degeneracy $N$ and a Hubbard Coulomb interaction without multiplet effects.
Arfken +5 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Paulownia Tree as an Alternative Raw Material for Pencil Manufacturing
BioResources, 2015 The Paulownia tree is one of the most important fast growing species in the World and is an ideal multipurpose tree. In this study, the potential use of Paulownia wood (Paulownia elongata) as a raw material for the pencil manufacturing industry is ...
Bulent Kaygin +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source