Results 121 to 130 of about 1,238,129 (264)

PETG as an Alternative Material for the Production of Drone Spare Parts. [PDF]

Polymers (Basel)
Baltić MZ, Vasić MR, Vorkapić MD, Bajić DM, Piteľ J, Svoboda P, Vencl A.   +6 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Synthesis, physical characteristics, and biocompatibility test of chitosan-alginate-fucoidan scaffold as an alternative material for alveolar bone substitution. [PDF]

BMC Oral Health
Hamrun N, Herdianto N, Gustiono D, Oktawati S, Kamil K, Marlina E, Ibriana I, Nurfaizah T, Arif AR, Azalia F, Hasanuddin H.   +10 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Waterproof Flexible Polymer-Functionalized Graphene-Based Piezoresistive Strain Sensor for Structural Health Monitoring and Wearable Devices

ACS Omega, 2020
Vetrivel Sankar, Ashwin Nambi, Vivek Nagendra Bhat, Debadatta Sethy, Krishnan Balasubramaniam, Sumitesh Das, Mriganshu Guha, Ramaprabhu Sundara   +7 more
doaj   +1 more source

Vaginal host response to polycarbonate urethane, an alternative material for the repair of pelvic organ prolapse. [PDF]

Acta Biomater
Knight K, Breedlove S, Obisesan T, Egnot M, Daneshdoost N, King G, Meyn L, Gall K, Moalli P.   +8 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Sol-gel derived ceramic nanoparticles as an alternative material for microstrip patch antenna in WLAN applications. [PDF]

Sci Rep
Didde S, Dubey RS.
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Alternative material recommendation for facade cladding: High silica-containing stonepaste ceramics. [PDF]

Heliyon
Dereli M, Öztürk Ç.
europepmc   +1 more source