Results 61 to 70 of about 1,238,129 (264)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Chemical Composition of Straw as an Alternative Material to Wood Raw Material in Fibre Isolation
Drvna Industrija, 2016 Wood is still the most widely used raw material for pulp and paper production in the world. However, due to the necessity to supply the paper industry with raw materials used in the extraction of cellulose fibres and the overexploitation of forests, new ...
Željka Barbarić-Mikočević +1 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Alternative X-ray attenuation material from iodide-starch-gel-based materials
Journal of Associated Medical SciencesBackground: Iodine is often used as a contrast media because the k-shell binding energy (K-edge) is 33.2 keV, the average energy of a diagnostic X-ray. Thus, iodine can be utilized as a radiation attenuation material for X-rays.
Nutjaree Suriya +4 more
doaj +1 more source
Insects feeding on cadavers as an alternative source of human genetic material
Archives of Forensic Medicine and Criminology, 2015 In some criminal cases, the use of classical sources of human genetic material is difficult or even impossible. One solution may be the use of insects, especially blowfly larvae which feed on corpses.
Rafał Skowronek +3 more
doaj +1 more source
Bacterial Nanocellulose Hydrogel: A Promising Alternative Material for the Fabrication of Engineered Vascular Grafts. [PDF]
Polymers (Basel), 2023 Liu D, Meng Q, Hu J.
europepmc +1 more source
QUANTUM INTERACTIVE DUALISM: AN ALTERNATIVE TO MATERIALISM [PDF]
Zygon: Journal of Religion and Science, 2006 Abstract. René Descartes proposed an interactive dualism that posits an interaction between the mind of a human being and some of the matter in his or her brain. However, the classical physical theories that reigned during the eighteenth and nineteenth centuries are based exclusively on the material/physical part of Descartes' ontology, and they ...
openaire +2 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source