Results 101 to 110 of about 786,469 (327)
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Two new feature selection metrics for text classification
Automatika, 2019 Obtaining meaningful information from data has become the main problem. Hence data mining techniques have gained importance. Text classification is one of the most commonly studied areas of data mining.
Durmuş Özkan Şahin, Erdal Kılıç
doaj +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Decomposing Inequality and Social Welfare Changes: The Use of Alternative Welfare Metrics [PDF]
This paper presents two 'non-welfarist' approaches and one 'welfarist' approach to decompose changes in inequality and social welfare into three components. We distinguish the contributions of population, tax policy and labour supply behavioural effects.
John Creedy, Nicolas Hérault
core
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Erratum: Viability of AMURA biomarkers from single-shell diffusion MRI in clinical studies
Frontiers in Neuroscience, 2023 Frontiers Production Office
doaj +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Mapping the Generations of Research Impact Science: A Scoping Review of Metrics, Frameworks, and Predictive Approaches [PDF]
Journal of Library and Information StudiesThis scoping review systematically examines the evolution of research impact assessment frameworks, categorising their development into 4 generations.
Mudassar Arsalan +2 more
doaj +1 more source
An Alternative Variational Principle for Geodesics of a Randers Metric
Advanced Nonlinear Studies, 2009 Abstract We present an alternative variational principle for the geodesics of a Randers metric. We define a functional I on the manifold of H1,2 curves joining two points on a Randers manifold (M, F) defined by a Riemannian metric g and a differential form ω.
openaire +3 more sources